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https://www.ncbi.nlm.nih.gov/pubmed/31990066
Jan 28, 2020 · 1. J Cell Physiol. 2020 Jan 28. doi: 10.1002/jcp.29562. [Epub ahead of print] Overexpression of CFL1 in gastric cancer and the effects of its silencing by siRNA with a nanoparticle delivery system in the gastric cancer cell line.
https://www.nature.com/articles/srep21881
Feb 24, 2016 · In conclusion, this is the first study to develop and show that receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient and safe non-viral siRNA delivery system …Author: Yu-Wai-Man C, Tagalakis Ad, Manunta, Hart Sl, Khaw Pt
https://www.sciencedirect.com/science/article/pii/S1818087614000646
4.4. Conjugate siRNA delivery systems for cancer therapy. Directly conjugation of delivery materials to siRNA has been shown to be a promising system for siRNA delivery. The most common conjugate materials are small drug molecules, aptamers, lipids, peptides, proteins and polymers . This system has a quite obvious advantage for cancer ...Author: Cong-fei Xu, Jun Wang
https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.29562
Overexpression of CFL1 in gastric cancer and the effects of its silencing by siRNA with a nanoparticle delivery system in the gastric cancer cell line. Seyedeh Saideh Daryabari. Department of Animal Biology, University of Tabriz, Tabriz, Iran. Search for more papers by this author.Author: Seyedeh Saideh Daryabari, Marziyeh Fathi, Majid Mahdavi, Yaghoub Moaddab, Mohammad Ali Hosseinpour F...
https://www.sigmaaldrich.com/life-science/functional-genomics-and-rnai/sirna/nter.html
Sigma’s N-TER Nanoparticle siRNA Transfection System is based on a peptide transfection reagent specifically designed to bypass these limitations and allow for efficient delivery of siRNAs into these historically recalcitrant eukaryotic cell types.
https://www.researchgate.net/publication/309582244_Nanoparticle_delivery_systems_for_siRNA-based_therapeutics
Even though nanoparticle-mediated siRNA delivery has opened a totally new approach to deal with deadly diseases, it also suffers from barriers such as rapid clearance from the circulation by RES ...
https://www.hindawi.com/journals/jnm/2011/742895/
Despite the powerful therapeutic potential of siRNA, there are challenges for developing efficient and specific delivery systems for systemic administration. There are extracellular and intracellular barriers for nanoparticle-mediated delivery. First, nanoparticles are rapidly cleared from the circulation by the reticuloendothelial system (RES).Author: Shutao Guo, Leaf Huang
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