We have collected information about Sirna Delivery 2015 for you. Follow the links to find out details on Sirna Delivery 2015.
https://www.nature.com/articles/s41573-019-0017-4
Mar 07, 2019 · Cuellar, T. L. et al. Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB–siRNA conjugates. Nucleic Acids Res. 43 , 1189–1203 (2015). CASAuthor: Ryan L. Setten, Ryan L. Setten, John J. Rossi, John J. Rossi, Si-ping Han, Si-ping Han
https://www.sciencedirect.com/science/article/pii/S1818087614000646
If siRNA delivery provokes unacceptable toxicity on either a cellular or systemic level, even the most efficacious siRNA delivery system will be rendered useless. Viral vectors, which were among the first vehicles to be studied for siRNA delivery, can induce unacceptable levels of toxicity through the activation of immune responses .Author: Cong-fei Xu, Jun Wang
https://pubs.acs.org/doi/abs/10.1021/jacs.5b03429
The ability to control chemical functionality is an exciting feature of modern polymer science that enables precise design of drug delivery systems. Ring-opening polymerization of functional monomers has emerged as a versatile method to prepare clinically translatable degradable polyesters.1 A variety of functional groups have been introduced into lactones; however, the direct polymerization ...Author: Jing Hao, Petra Kos, Kejin Zhou, Jason B. Miller, Lian Xue, Yunfeng Yan, Hu Xiong, Sussana Elkassih,...
https://www.sciencedirect.com/science/article/pii/S174801321500078X
The different strategies developed for efficient siRNA delivery can be grouped in two categories: those involving a chemical modification of the siRNA and those mediating the delivery by exogenous compounds, such as aptamers, liposomes, nanoparticles (NPs), polymers, dendrimers, all requiring a specific chemistry to preserve the biological ...Author: Joao Conde, Joao Conde, Alfredo Ambrosone, Yulan Hernandez, Furong Tian, Mark McCully, Catherine C. ...
https://pubs.acs.org/doi/10.1021/mp200481g
Cell penetrating peptides (CPPs) are short strands of arginine- and/or lysine-rich peptides (<30 amino acids) that use their cationic nature for efficient intracellular accumulation. CPPs have been used for small interfering RNA (siRNA) delivery by direct complexation with the siRNA anionic phosphate backbone. During this process, however, part of the CPP cationic charges are neutralized, and ...
https://www.nature.com/articles/gt2014116
Jan 08, 2015 · These results suggest that the TGF-β1-siRNA delivery system with NPs described here could be an effective therapeutic option for PF in subjects undergoing PD. ... 08 January 2015; TGF-β …Author: H Yoshizawa, Y Morishita, M Watanabe, K Ishibashi, S Muto, E Kusano, D Nagata
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946317/
Nov 18, 2015 · However, effective and specific delivery of siRNA therapeutics to bone and bone-specific cells in vivo is very challenging. To realize the full therapeutic potential of siRNA in treating bone disorders, a safe and efficient, tissue- and cell-specific delivery system must be developed. ... J Bone Miner Res, 2015, 30 (2): 286-296.Author: Xinli Liu
https://www.ncbi.nlm.nih.gov/pubmed/26220182
Sep 18, 2015 · One approach to improve delivery is to identify small molecules enhancing these steps. It is unclear to what extent such enhancers can be universally applied to different delivery systems and cell types. Here, we performed a compound library screen on two well-established siRNA delivery systems, lipid nanoparticles and cholesterol conjugated ...Author: Jerome Gilleron, Prasath Paramasivam, Anja Zeigerer, William Querbes, Giovanni Marsico, Cordula Andr...
https://onlinelibrary.wiley.com/doi/pdf/10.1002/adfm.201403680
In the in vitro treatment of poly‐siRNA‐proteinticle complex, both of the tumor cell targeting and penetrating peptides are important for efficient delivery of siRNA, and the red fluorescent protein (RFP) expression in RFP‐expressing tumor cells is notably suppressed by the delivered siRNA with the complementary sequence to RFP mRNA.Author: Eun Jung Lee, Eun Jung Lee, So Jin Lee, Yoon Sik Kang, Ju Hee Ryu, Koo Chul Kwon, Eunji Jo, Ji Young...
http://onlinelibrary.wiley.com/doi/10.1002/adfm.201404629/abstract
May 11, 2015 · May 13, 2015 Pages 2646–2659 ... Cationic Polymer Modified Mesoporous Silica Nanoparticles for Targeted siRNA Delivery to HER2 + Breast Cancer. Authors. Worapol Ngamcherdtrakul, Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA ...
Searching for Sirna Delivery 2015?
You can just click the links above. The data is collected for you.
