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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572212/
May 24, 2019 · Background and Objectives: Lipid-based self-nanoemulsifying drug delivery systems (SNEDDS) have resurged the eminence of nanoemulsions by modest adjustments and offer many valuable opportunities in drug delivery. Chlorpromazine, an antipsychotic agent with poor aqueous solubility—with extensive first-pass metabolism—can be a suitable candidate for the development of …Author: Jeand Baloch, Muhammad Farhan Sohail, Hafiz Shaib Sarwar, Maria Hassan Kiani, Gul Majid Khan, Sarwat...
https://www.medscape.com/viewarticle/734501_6
Nov 01, 2019 · Self-nanoemulsifying drug delivery systems (SNEDDS) are nanoemulsion preconcentrates or anhydrous forms of nanoemulsion. These systems are anhydrous isotropic mixtures of oil, surfactant(s) and ...
https://www.sciencedirect.com/science/article/pii/B9780128136874000128
Formulation of lipid-based nanocarriers, such as self-nanoemulsifying drug delivery systems (SNEDDS) and self-microemulsifying drug delivery systems (SMEDDS) have received a lot of attention in recent years as an approach for overcoming poor solubility and oral bioavailability of drugs.Author: Marko Krstić, Đorđe Medarević, Jelena Đuriš, Svetlana Ibrić
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040505/
The aim is to prepare phosal based self nanoemulsifying drug delivery system (SNEDDS) for water insoluble drug zaltoprofen. Methods: The various parameters like solubility of drug in different vehicles, ternary phase diagram are considered to formulate the stable emulsion which is further characterized by Self emulsification time and globule ...
https://www.sciencedirect.com/science/article/pii/S0378517320301642
To improve the solubility and cell permeation of SEN, self-nanoemulsifying drug delivery systems (SNEDDSs) were developed. Capryol PGMC®, which showed the highest solubilization capacity, was selected as the oil. The self-emulsification ability of two surfactants, viz., Cremophor-EL® and Tween® 80, was compared.Author: Aristote B. Buya, Aristote B. Buya, Bernard Ucakar, Ana Beloqui, Patrick B. Memvanga, Véronique Préa...
https://www.hindawi.com/journals/bmri/2018/6763057/
It could be concluded that self-nanoemulsifying drug delivery system of tetrandrine has the potential to improve the dissolution and oral bioavailability of poor water-soluble Tet. Data Availability. The data used to support the findings of this study are available from the corresponding author upon request.Author: Chunxia Liu, Li Lv, Wei Guo, Lan Mo, Yaoxing Huang, Guocheng Li, Xingzhen Huang
https://journal.pda.org/content/67/3/201
May 01, 2013 · The objective of the present investigation was to develop and characterize the self-nanoemulsifying drug delivery system (SNEDDS) of glimepiride, a poorly soluble drug. Solubility of glimepiride in various vehicles was determined, and ternary phase diagrams were constructed using a suitable oil, surfactant, and cosurfactant system to find out the efficient self-emulsification system. A …Author: Shah, Parikh Rh, Chavda, Sheth Nr
https://www.medscape.com/viewarticle/734501_12
Oct 19, 2019 · Learn about self-nanoemulsifying drug delivery systems--one of the many ways by which nanotechnology can improve delivery and therapeutic efficacy of drugs.
https://www.tandfonline.com/doi/abs/10.1080/17425247.2016.1224845
Mar 27, 2014 · (2016). Solid super saturated self-nanoemulsifying drug delivery system (sat-SNEDDS) as a promising alternative to conventional SNEDDS for improvement rosuvastatin calcium oral bioavailability. Expert Opinion on Drug Delivery: Vol. 13, No. 11, pp. 1513-1521.Author: Hadel A. Abo Enin, Hend Mohamed Abdel-Bar
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