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https://www.news-medical.net/health/Resveratrol-Delivery.aspx
Aug 23, 2018 · With all the hype surrounding resveratrol’s anti-aging effects, a central problem remains, namely, its poor bioavailability. Different approaches have been taken to solve this problem, but not ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935991/
Development of a Lozenge for Oral Transmucosal Delivery of Trans-Resveratrol in Humans: ... tRES is uncharged at physiological pH which will allow passive diffusion across the buccal mucosa ... Future Applications of Oral Transmucosal Delivery of Trans-resveratrol.Author: Otis L. Blanchard, Gregory Friesenhahn, Martin A. Javors, James M. Smoliga
https://www.longecity.org/forum/topic/23733-buccal-delivery-superior/
Aug 13, 2008 · "The most efficient way of administering resveratrol in humans appears to be buccal delivery, that is without swallowing, by direct absorption through the inside of the mouth. When 1 mg of resveratrol in 50 mL solution was retained in the mouth for 1 min before swallowing, 37 ng/ml of free resveratrol were measured in plasma 2 minutes later.
https://www.ncbi.nlm.nih.gov/pubmed/28745229
Feb 14, 2018 · OBJECTIVE: In this study, we hypothesised that resveratrol could act prophylactically and/or treat inflammatory lesions of the oral cavity after being delivered by two different formulations of buccal mucoadhesive tablets (F1 and F2, which differed in terms of viscosity agents used).Author: Isadora Conde Ferreira Martins, Nadia Rezende Barbosa Raposo, Hanny Reis Mockdeci, Hudson Caetano Po...
https://www.reddit.com/r/Nootropics/comments/1mcpaz/how_to_increase_bioavailability_of_resveratrol/
It appears the liver removes most of the resveratrol that is delivered orally. 1, 2 So I would like to take it sublingual or perhaps buccal. I can't find many studies on it, but I have seen one where sublingual administration of resveratrol increases bioavailability when combined with alcohol 5. I can't find the direct link at the moment, so wikipedia will have to suffice.
http://www.eurekaselect.com/154482/article
Abstract: Background: Resveratrol is a polyphenol that has gained momentum in therapeutics in the last few years. Objective: In this study, we hypothesised that resveratrol could act prophylactically and/or treat inflammatory lesions of the oral cavity after being delivered by two different formulations of buccal mucoadhesive tablets (F1 and F2, which differed in terms of viscosity agents used).Author: Isadora Conde Ferreira Martins, Nadia Rezende Barbosa Raposo, Hanny Reis Mockdeci, Hudson Caetano Po...
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