Quantitative Analysis Of Physiological Processes And Drug Delivery

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Quantitative analysis of drug delivery to the brain via ...

    https://www.sciencedirect.com/science/article/pii/S0168365914004623
    The major descriptive and quantitative analysis outcomes of selected publications were summarized. The analyzed parameters included information regarding the publication trends in the field of intranasal drug delivery, properties of the drugs and drug formulations, and experimental settings of the identified studies.Author: Luba Kozlovskaya, Mohammed Abou-Kaoud, David Stepensky

Quantitative prediction of human pharmacokinetic responses ...

    https://www.nature.com/articles/s41551-019-0498-9
    Jan 27, 2020 · The quantitative in-vitro-to-in-vivo translation of PK and PD parameters and the prediction of drug absorption, distribution, metabolism, excretion and …Author: Anna Herland, Anna Herland, Anna Herland, Ben M. Maoz, Debarun Das, Mahadevabharath R. Somayaji, Rac...

Chemotherapeutic Drug Delivery and Quantitative Analysis ...

    https://pubs.acs.org/doi/full/10.1021/acsbiomaterials.8b00877
    We show that the mode of drug delivery influences uptake in the vessel endothelium and tumor cells. Through quantification of endothelial and tumor cell proliferation, apoptosis, and motility, we profile the kinetics of drug action with mechanisms of drug transport across the vessel lumen and into the surrounding matrix.Author: Andrew D. Wong, Luisa M. Russell, Moriah E. Katt, Peter C. Searson

Microscopy Based Quantitative Analysis of Drug Delivery ...

    https://www.cambridge.org/core/journals/microscopy-and-microanalysis/article/microscopy-based-quantitative-analysis-of-drug-delivery-process/578937D9F6F875737BF659199E589CAE
    Microscopy Based Quantitative Analysis of Drug Delivery Process - Volume 18 Issue S2 - P. Morse, R. Lee, E. Lee, J. Bodycomb, S. Mamedov Skip to main content We use cookies to distinguish you from other users and to provide you with a better experience on our websites.Author: P. Morse, R. Lee, E. Lee, J. Bodycomb, S. Mamedov

Quantitative micro-Raman analysis of micro-particles in ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592161/
    Apr 01, 2019 · Here, we explored Raman spectroscopy as a quantitative technique of analysis of polymeric microplates (μPL) for drug delivery. Microplates are compound reservoirs for local application and delivery of therapeutics. With a size comparable with cell dimensions, i.e. 20 × 20 μm in length and 5 μm in height, they are visible by optical microscopy. In the present study, microplates …Author: Daniele Di Mascolo, Alessandro Coclite, Francesco Gentile, Marco Francardi

Quantitative Systems Pharmacology, Volume 42 - 1st Edition

    https://www.elsevier.com/books/quantitative-systems-pharmacology/manca/978-0-444-63964-6
    Multiscale models for transport and biodistribution of therapeutics in cancer. 8. Quantitative systems pharmacology on cancer drug delivery to target sites: Application of chemical engineering tools. 9. Systems engineers’ role in biomedical research.

Quantitative analysis of drug delivery to the brain via ...

    https://www.researchgate.net/publication/263710204_Quantitative_analysis_of_drug_delivery_to_the_brain_via_nasal_route
    Request PDF Quantitative analysis of drug delivery to the brain via nasal route The blood–brain barrier (BBB) prevents drugs' permeability into the brain and limits the management of brain ...

Drug Delivery - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/engineering/drug-delivery
    Drug delivery is a process of administering a pharmaceutical compound to bring about therapeutic effects in patients. Drug delivery technology evolved to become an integral tool for the enhancement of pharmacoki-netic properties of drugs, minimization of harmful side effects, and bringing about superior clinical outcomes.

Qualitative and Quantitative Analysis of Lateral Diffusion ...

    https://www.researchgate.net/publication/324468682_Qualitative_and_Quantitative_Analysis_of_Lateral_Diffusion_of_Drugs_in_Human_Skin
    In in vitro permeation studies, laser ablation resulted in a significant increase in the drug cumulative delivery, flux, and permeability coefficient as compared to the untreated group (n=3, p<0.05).

Basic Fundamentals of Drug Delivery ScienceDirect

    https://www.sciencedirect.com/book/9780128179093/basic-fundamentals-of-drug-delivery
    Drug delivery to the brain is extremely restricted and controlled by the occurrence of the blood–brain barrier (BBB), which prevents the movement of about 98% of drugs and pharmaceuticals. This effect is caused due to the epithelial-like tight junctions (TJ) nature inside the brain endothelium.

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