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https://www.sciencedirect.com/science/article/pii/S0168365914004623
The major descriptive and quantitative analysis outcomes of selected publications were summarized. The analyzed parameters included information regarding the publication trends in the field of intranasal drug delivery, properties of the drugs and drug formulations, and experimental settings of the identified studies.Author: Luba Kozlovskaya, Mohammed Abou-Kaoud, David Stepensky
https://www.nature.com/articles/s41551-019-0498-9
Jan 27, 2020 · The quantitative in-vitro-to-in-vivo translation of PK and PD parameters and the prediction of drug absorption, distribution, metabolism, excretion and …Author: Anna Herland, Anna Herland, Anna Herland, Ben M. Maoz, Debarun Das, Mahadevabharath R. Somayaji, Rac...
https://pubs.acs.org/doi/full/10.1021/acsbiomaterials.8b00877
We show that the mode of drug delivery influences uptake in the vessel endothelium and tumor cells. Through quantification of endothelial and tumor cell proliferation, apoptosis, and motility, we profile the kinetics of drug action with mechanisms of drug transport across the vessel lumen and into the surrounding matrix.Author: Andrew D. Wong, Luisa M. Russell, Moriah E. Katt, Peter C. Searson
https://www.cambridge.org/core/journals/microscopy-and-microanalysis/article/microscopy-based-quantitative-analysis-of-drug-delivery-process/578937D9F6F875737BF659199E589CAE
Microscopy Based Quantitative Analysis of Drug Delivery Process - Volume 18 Issue S2 - P. Morse, R. Lee, E. Lee, J. Bodycomb, S. Mamedov Skip to main content We use cookies to distinguish you from other users and to provide you with a better experience on our websites.Author: P. Morse, R. Lee, E. Lee, J. Bodycomb, S. Mamedov
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592161/
Apr 01, 2019 · Here, we explored Raman spectroscopy as a quantitative technique of analysis of polymeric microplates (μPL) for drug delivery. Microplates are compound reservoirs for local application and delivery of therapeutics. With a size comparable with cell dimensions, i.e. 20 × 20 μm in length and 5 μm in height, they are visible by optical microscopy. In the present study, microplates …Author: Daniele Di Mascolo, Alessandro Coclite, Francesco Gentile, Marco Francardi
https://www.elsevier.com/books/quantitative-systems-pharmacology/manca/978-0-444-63964-6
Multiscale models for transport and biodistribution of therapeutics in cancer. 8. Quantitative systems pharmacology on cancer drug delivery to target sites: Application of chemical engineering tools. 9. Systems engineers’ role in biomedical research.
https://www.researchgate.net/publication/263710204_Quantitative_analysis_of_drug_delivery_to_the_brain_via_nasal_route
Request PDF Quantitative analysis of drug delivery to the brain via nasal route The blood–brain barrier (BBB) prevents drugs' permeability into the brain and limits the management of brain ...
https://www.sciencedirect.com/topics/engineering/drug-delivery
Drug delivery is a process of administering a pharmaceutical compound to bring about therapeutic effects in patients. Drug delivery technology evolved to become an integral tool for the enhancement of pharmacoki-netic properties of drugs, minimization of harmful side effects, and bringing about superior clinical outcomes.
https://www.researchgate.net/publication/324468682_Qualitative_and_Quantitative_Analysis_of_Lateral_Diffusion_of_Drugs_in_Human_Skin
In in vitro permeation studies, laser ablation resulted in a significant increase in the drug cumulative delivery, flux, and permeability coefficient as compared to the untreated group (n=3, p<0.05).
https://www.sciencedirect.com/book/9780128179093/basic-fundamentals-of-drug-delivery
Drug delivery to the brain is extremely restricted and controlled by the occurrence of the blood–brain barrier (BBB), which prevents the movement of about 98% of drugs and pharmaceuticals. This effect is caused due to the epithelial-like tight junctions (TJ) nature inside the brain endothelium.
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