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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467685/
Nov 01, 2003 · Poly[methacrylic acid-grafted-poly(ethylene glycol)] [P(MAA-g-EG)] is a complexation hydrogel molecularly designed for oral peptide delivery.In this work, the cytotoxicity and insulin-transport enhancing effect of P(MAA-g-EG) microparticles on intestinal epithelial cells were evaluated using Caco-2 cell monolayers.A series of P(MAA-g-EG) microparticles with different polymer compositions were ...Author: Hideki Ichikawa, Nicholas A. Peppas
https://pubs.acs.org/doi/10.1021/cr200157d
In-situ mineralization of calcium carbonate in pectin based edible hydrogel for the delivery of protein at colon. Journal of Drug Delivery Science and Technology 2019, 53, 101137. DOI: 10.1016/j.jddst.2019.101137. Mehmet Can, Ramesh S. Ayyala, Nurettin Sahiner.Author: Tina Vermonden, Roberta Censi, Wim E. Hennink
https://www.sciencedirect.com/science/article/pii/S0022354915508575
Research Articles Oral delivery of insulin using pH†responsive complexation gels A.M. Lowman, †‡ M. Morishita, § M. Kajita, § T. Nagai, § N.A. Peppas, * ‡ ‡ Biomaterials and Drug Delivery Laboratories, School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907.Author: A.M. Lowman, M. Morishita, M. Kajita, T. Nagai, N.A. Peppas
http://biomat.bme.utexas.edu/research/delivery.htm
Drug and Protein Delivery . Our group originated and is the leading proponent of the use of hydrophilic polymers and hydrogels for the controlled delivery of drugs, peptides, and proteins.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467730/
Feb 21, 2006 · Novel oral insulin delivery systems based on complexation polymer hydrogels: Single and multiple administration studies in type 1 and 2 diabetic rats ... which is the most widely used formulation strategy for peptide and protein delivery systems. To date, various polymeric carriers have been used to develop such drug delivery systems, however ...Author: Mariko Morishita, Takahiro Goto, Koji Nakamura, Anthony M. Lowman, Kozo Takayama, Nicholas A. Peppas
https://www.sciencedirect.com/science/article/pii/S0168365999000279
Poly(ethylene glycol)-containing hydrogels in drug delivery. ... Understanding of PEG-containing carrier/mucosal adhesion is of utmost importance in local protein delivery, especially in the upper small intestine. ... A.M LowmanProtein delivery from novel bioadhesive complexation hydrogels. S Frøkjaer, L Christup, P Krogsgaard-Larsen (Eds ...Author: Nikolaos A Peppas, Kelley B Keys, Madeline Torres-Lugo, Anthony M Lowman
http://europepmc.org/articles/PMC4467685
Nov 01, 2003 · Novel complexation hydrogels for oral peptide ... Morishita M, Peppas NA, Nagai T. Novel bioadhesive complexation networks for oral protein drug delivery. In: McCulloch I, Shalaby SW, editors. ... Protein delivery from novel bioadhesive complexation hydrogels. In: Frokjaer S, Christup L, Krogsgaard-Larsen P, editors. Protein and peptide drug ...Author: Hideki Ichikawa, Nicholas A. Peppas
https://www.researchgate.net/publication/6121101_Lectin_functionalized_complexation_hydrogels_for_oral_protein_delivery
Lectin functionalized complexation hydrogels for oral protein delivery Article in Journal of Controlled Release 116(2):e66-8 · December 2006 with 13 Reads How we measure 'reads'
https://www.researchgate.net/publication/7248311_Novel_delivery_system_based_on_complexation_hydrogels_as_delivery_vehicles_for_insulin-transferrin_conjugates
Novel delivery system based on complexation hydrogels as delivery vehicles for insulin-transferrin conjugates Article in Biomaterials 27(20):3846-54 · August 2006 with 9 Reads How we measure 'reads'
https://www.semanticscholar.org/paper/Oral-delivery-of-insulin-using-pH-responsive-gels.-Lowman-Morishita/41000d403de50df829eb108fecf92af9f8774905
1999; DOI: 10.1021/js980337n Oral delivery of insulin using pH-responsive complexation gels. @article{Lowman1999OralDO, title={Oral delivery of insulin using pH-responsive complexation gels.}, author={Anthony M. Lowman and Mariko Morishita and Masahiro Kajita and Tsuneji Nagai and Nicholas A Peppas}, journal={Journal of pharmaceutical sciences}, year={1999}, volume={88 9}, pages={ 933-7 } }
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