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https://www.tandfonline.com/doi/abs/10.1517/17425247.2.1.53
Oct 20, 2008 · Propellant-driven metered-dose inhalers for pulmonary drug delivery. The current market for pulmonary drug delivery is at a bottleneck. The therapeutic advantages of inhalation aerosols, and the potential for the lungs as a route for systemically acting drugs, vaccines and gene therapeutic agents, have resulted in a rapid growth of the industry.Author: Hugh Dc Smyth
https://researchers.dellmed.utexas.edu/en/publications/propellant-driven-metered-dose-inhalers-for-pulmonary-drug-delive
Propellant-driven metered-dose inhalers for pulmonary drug delivery. Hugh D Smyth. College of Pharmacy; Research output: Contribution to journal › Review article. 33 Citations (Scopus) Abstract. The current market for pulmonary drug delivery is at a bottleneck. The therapeutic advantages of inhalation aerosols, and the potential for the lungs ...Author: Hugh Dc Smyth
https://www.researchgate.net/publication/7471360_Propellant-driven_metered-dose_inhalers_for_pulmonary_drug_delivery
The pressurized, propellant driven metered-dose inhaler is an essential technology for pulmonary drug delivery.
https://onlinelibrary.wiley.com/doi/abs/10.1002/9781118833322.ch10
Mar 25, 2016 · The devices that are employed to deliver drugs to the lungs may be divided into three categories: propellant‐driven metered‐dose inhalers (pMDIs), dry powder inhalers (DPIs), and nebulizers. Each of these systems delivers aerosols by a different principle, and the chemistry associated with the product varies significantly between them.Author: Anthony J. Hickey
https://www.sciencedirect.com/science/article/pii/S0378517399001325
Systemic drug delivery via pressurized metered dose inhalers Propellant driven aerosols can be used for the systemic delivery of peptides, e.g. the LHRH analogue leuprolide ( Wood and Knowles, 1994 ), proteins (e.g. bovine gammaglobulin), vaccines to the respiratory tract and DNA-plasmids ( …Author: Manfred Keller
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/metered-dose-inhaler
Metered-Dose Inhaler Metered-dose inhaler is an inhaler device with specified doses that provides a certain dose of the active agent in each puff. From: Nanostructures for Drug Delivery, 2017
https://www.dovepress.com/inhalation-drug-delivery-devices-technology-update-peer-reviewed-fulltext-article-MDER
Inhalation drug delivery devices: technology update Mariam Ibrahim, Rahul Verma, Lucila Garcia-ContrerasDepartment of Pharmaceutical Sciences, College of Pharmacy, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USAAbstract: The pulmonary route of administration has proven to be effective in local and systemic delivery of miscellaneous drugs and biopharmaceuticals …
https://www.researchgate.net/publication/337038720_Pulmonary_Drug_Delivery
A review is provided of delivery mechanisms and design of the three major classes of pulmonary drug delivery devices (pressurized metered dose inhalers, nebulizers, and dry powder inhalers).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334339/
Feb 12, 2015 · Pulmonary drug delivery is an attractive route of administration for diverse entities including micro and macromolecules such as vaccines, DNA, cytokines, antibodies, and hormones.16 Therefore, it is essential that the hardware technology of inhalers meets the needs of the pulmonary delivery of such diverse molecules. Devices should be ...Author: Mariam Ibrahim, Rahul Verma, Lucila Garcia-Contreras
https://www.pharmatutor.org/articles/pulmonary-drug-delivery-a-review
Inhaled drug delivery puts drug where it is needed. 2. It requires low and fraction of oral dose i.e. drug content of one 4 mg tablet of salbutamol equals to 40 doses of meter doses. 3. Pulmonary drug delivery having very negligible side effects since rest of body is not exposed to drug.
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