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https://www.researchgate.net/publication/322930891_PRODRUGS_A_REVIEW
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http://ajrconline.org/HTMLPaper.aspx?Journal=Asian%20Journal%20of%20Research%20in%20Chemistry;PID=2009-2-2-2
Asian Journal of Research in Chemistry. Delivering full text access to the world's highest quality literature.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751454/
Feb 05, 2008 · Chemical Drug Delivery Systems. A successful prodrug approach that utilizes improved lipophilicity and also requires a sequential bioactivation steps for conversion to an active drug and a brain tissue trapped intermediate is often referred in the literature as a chemical drug delivery system (CDS; 34–37). The CDS term was originally coined ...Author: Jarkko Rautio, Krista Laine, Mikko Gynther, Jouko Savolainen
https://www.nature.com/articles/nrd2468
Mar 01, 2008 · This Review provides an overview of functional groups that are amenable to prodrug design, and highlights major applications of the prodrug …Author: Jarkko Rautio, Hanna Kumpulainen, Tycho Heimbach, Reza Oliyai, Dooman Oh, Tomi Järvinen, Jouko Savol...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407659/
Chemical modification such as prodrug targeting various nutrient transporters (amino acids, peptide and vitamin) has evolved a great deal ofintereSt to improve ocular drug delivery. In this review, we have discussed various prodrug strategies which have been widely applied for enhancing therapeutic efficacy of ophthalmic drugs.Author: Megha Barot, Mahuya Bagui, Mitan R. Gokulgandhi, Ashim K. Mitra
http://if-pan.krakow.pl/pjp/pdf/2013/1_1.pdf
Prodrug concept The basic aim of prodrug design is to mask undesir-able drug properties, such as low solubility in water or lipid membranes, low target selectivity, chemical in-stability, undesirable taste, irritation or pain after local administration, presystemic metabolism and toxicity [54, 70, 74]. In general, the rationale behind the use of
https://www.researchgate.net/publication/335902831_Carriers_for_Prodrug_Synthesis_A_Review
This review deals with the Rational for design of polymer-drug conjugates, requirements for selection of drug candidate for polymeric prodrug, requirements for selecting polymers as candidate drug ...
https://pubs.acs.org/doi/10.1021/jm0602155
Nov 08, 2006 · Magnetic responsive of paclitaxel delivery system based on SPION and palmitoyl chitosan. Journal of Magnetism and Magnetic Materials 2017, 421, 316-325. DOI: 10.1016/j.jmmm.2016.07.066. Zijun Zhou, Jingzhe Yan, Tingting Sun, Xin Wang, Zhigang Xie. Nanoprodrug of retinoic acid-modified paclitaxel.Author: Mariusz Skwarczynski, Yoshio Hayashi, Yoshiaki Kiso
https://www.ijpsonline.com/articles/carriers-for-prodrug-synthesis-a-review-3634.html
The prodrug approach is rapidly becoming a crucial part in the stratagem of delivery of drugs. The prodrug strategy implementation in the last 20 y has led to a steady advancement in the biopharmaceutical, physicochemical and/or pharmacokinetic attributes of …Author: Preeti P. Mehta, A. R. Chabukswar, Swati C. Jagdale
https://www.nature.com/articles/nrd.2018.46
Apr 27, 2018 · In the past 10 years, the US Food and Drug Administration has approved at least 30 prodrugs, which accounts for more than 12% of all approved small-molecule new chemical entities. In this Review ...Author: Jarkko Rautio, Nicholas A. Meanwell, Li Di, Michael J. Hageman
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