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https://pubs.acs.org/doi/full/10.1021/acsomega.8b00419
Porphyrin–Gold Nanomaterial for Efficient Drug Delivery to Cancerous Cells Kaushik Bera Structural Biology and Bioinformatics Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata 700032, IndiaAuthor: Kaushik Bera, Samarpan Maiti, Mritunjoy Maity, Chitra Mandal, Nakul C. Maiti
https://pubs.acs.org/doi/abs/10.1021/jm9007278
The porphyrin−cyclodextrin conjugates were prepared and tested for selective and effective multifunctional drug delivery and therapy. The porphyrin receptor system combines efficient binding of the selected drug to the cyclodextrin cavity and photosensitizing properties of the porphyrin moiety with high accumulation of the whole complex in cancer tissue.Author: Jarmila Králová, Zdeněk Kejík, Tomáš Bříza, Pavla Poučková, Aleš Král, Pavel Martásek, Vladimír Král
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988818/
The delivery of therapeutic compounds to target tissues is a central challenge in treating disease. Externally controlled drug release systems hold potential to selectively enhance localized delivery. Here we describe liposomes doped with porphyrin–phospholipid that are permeabilized directly by …
https://www.ncbi.nlm.nih.gov/pubmed/30075210
Sep 28, 2018 · Following intravenous administration, LIFU enhanced deposition of Dox within tumor tissue, suppressed tumor growth, and also increased porphyrin near infrared tumor fluorescence. Thus, pp-lipo is a versatile carrier that can be extended to many ultrasound-controllable drug delivery …Author: Xiaobing Wang, Xiaobing Wang, Fei Yan, Xiufang Liu, Pan Wang, Shuai Shao, Yue Sun, Zonghai Sheng, Qu...
https://www.sciencedirect.com/science/article/pii/S0168365918304516
Porphyrin-loaded liposomes have been described for various biological applications and the fluorescence imaging of porphyrin could serve as a sensitive tool to track drug delivery. The in vitro studies described above have demonstrated the pyro-lipid facilitated drug release from pp-lipo in response to US treatment.Author: Xiaobing Wang, Xiaobing Wang, Fei Yan, Xiufang Liu, Pan Wang, Shuai Shao, Yue Sun, Zonghai Sheng, Qu...
https://www.sciencedirect.com/science/article/abs/pii/S0168365918304516
Porphyrin-lipid conferred liposomes with ultrasound-responsive properties. Drug release from pp-lipo was spatiotemporally controlled by ultrasound exposure. Ultrasound facilitated pp-lipo imaging-guided deep penetration of cargos.
https://www.frontiersin.org/articles/10.3389/fphy.2015.00023/full
Apr 10, 2015 · This review examines recent research on porphyrin-derived materials in multimodal imaging, drug delivery, bio-sensing, phototherapy and probe design, demonstrating their bright future for biomedical applications.Author: Haoyuan Huang, Wentao Song, James Rieffel, Jonathan F. Lovell
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304552/
Although several biocompatible porous MOFs were explored as drug delivery, Zr 6 and porphyrin-based MOFs remain to be reported. Figure 1. Structural diagram. (a) schematic illustration for the construction of PCN-222 and (b) the chemical structure of Oridonin. Oridonin (Ori) is a ...Author: Xin Leng, Hongliang Huang, Wenping Wang, Na Sai, Na Sai, Longtai You, Xingbin Yin, Jian Ni
https://www.ncbi.nlm.nih.gov/pubmed/28553633
Emerging applications of porphyrins in photomedicine. ... dendrimers and silica nanoparticles have been explored for photosensitizer delivery. Concurrently, entirely new classes of porphyrin nanostructures are being developed, such as smart materials that are activated by specific biochemicals encountered at disease sites. ... , drug delivery ...
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