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https://www.ncbi.nlm.nih.gov/pubmed/25651103
Jan 15, 2015 · Here, a protocol for the preparation and use of a biocompatible and effective siRNA delivery system is presented. This platform consists of polyethylenimine (PEI) and arginine (Arg)-grafted porous silicon microparticles, which can be loaded with siRNA by performing a simple mixing step.Author: Jianliang Shen, Jianliang Shen, Xiaoyan Wu, Xiaoyan Wu, Yeonju Lee, Joy Wolfram, Zhizhou Yang, Zong ...
https://www.jove.com/video/52075/porous-silicon-microparticles-for-delivery-of-sirna-therapeutics
Delivery remains the main challenge for the therapeutic implementation of small interfering RNA (siRNA). This protocol involves the use of a multifunctional and biocompatible siRNA delivery platform, consisting of arginine and polyethylenimine grafted porous silicon microparticles. Cite this ArticleAuthor: Jianliang Shen, Jianliang Shen, Xiaoyan Wu, Xiaoyan Wu, Yeonju Lee, Joy Wolfram, Zhizhou Yang, Zong ...
https://www.researchgate.net/publication/272074845_Porous_Silicon_Microparticles_for_Delivery_of_siRNA_Therapeutics
Porous Silicon Microparticles for Delivery of siRNA Therapeutics Article (PDF Available) in Journal of Visualized Experiments · January 2015 with 105 Reads How we measure 'reads'
https://docksci.com/porous-silicon-microparticles-for-delivery-of-sirna-therapeutics_5a66c7d0d64ab2fed4f8e6e5.html
Journal of Visualized Experiments www.jove.com Video Article Porous Silicon Microparticles for Delivery of siRNA Therapeutics 1,2 1,3 1 1,4 1 2 1,5 Jianliang Shen* , Xiaoyan Wu* , Yeonju Lee , Joy Wolfram , Zhizhou Yang , Zong-Wan Mao , Mauro Ferrari , Haifa Shen
https://scholars.houstonmethodist.org/en/publications/porous-silicon-microparticles-for-delivery-of-sirna-therapeutics(dd473a83-6187-4322-a82c-29b47eaac2dd).html
title = "Porous silicon microparticles for delivery of siRNA therapeutics", abstract = "Small interfering RNA (siRNA) can be used to suppress gene expression, thereby providing a new avenue for the treatment of various diseases.Author: Jianliang Shen, Jianliang Shen, Xiaoyan Wu, Xiaoyan Wu, Yeonju Lee, Joy Wolfram, Zhizhou Yang, Zong ...
https://www.jove.com/video/52075/poroso-silicon-microparticelle-per-consegna-di-sirna-therapeutics?language=Italian
I piccoli RNA interferenti (siRNA) sono molecole a doppio filamento di RNA che possono sopprimere l'espressione dei geni. Negli ultimi anni, siRNAs sono stati sviluppati come una nuova generazione di biofarmaci che mostrano potenziale terapeutico per uso futuro in applicazioni cliniche 1-5. Tuttavia, il successo di una terapia siRNA resta una sfida considerevole, dovuta alla degradazione da ...
https://mayoclinic.pure.elsevier.com/en/publications/porous-silicon-microparticles-for-delivery-of-sirna-therapeutics
Here, a protocol for the preparation and use of a biocompatible and effective siRNA delivery system is presented. This platform consists of polyethylenimine (PEI) and arginine (Arg)-grafted porous silicon microparticles, which can be loaded with siRNA by performing a simple mixing step.Author: Jianliang Shen, Jianliang Shen, Xiaoyan Wu, Xiaoyan Wu, Yeonju Lee, Joy Wolfram, Zhizhou Yang, Zong ...
https://pubs.acs.org/doi/abs/10.1021/nn4035316
A novel strategy to fabricate doxorubicin/bovine serum albumin/porous silicon nanocomposites with pH-triggered drug delivery for cancer therapy in vitro. Journal of Materials Chemistry B 2014, 2 (32) , 5280. DOI: 10.1039/C4TB00307A. Da Ma. Enhancing endosomal escape for …Author: Jianliang Shen, Jianliang Shen, Rong Xu, Junhua Mai, Han Cheon Kim, Xiaojing Guo, Guoting Qin, Yong ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795885/
Biomedical applications of porous silicon include drug delivery, imaging, diagnostics and immunotherapy. This review summarizes new silicon particle fabrication techniques, dynamics of cellular transport, advances in the multistage vector approach to drug delivery, and …Author: David J Savage, David J Savage, David J Savage, Xuewu Liu, Steven A Curley, Mauro Ferrari, Rita E Se...
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