We have collected information about Polysialic Acid Drug Delivery for you. Follow the links to find out details on Polysialic Acid Drug Delivery.
https://www.sciencedirect.com/science/article/pii/S1818087614000105
Sialic acid/polysialic acid in the drug delivery systems In the history of drug delivery systems (DDS), carrier and drug molecules PEGylated (PEGylation) technology is regarded as a milestone. PEGylation nanoparticles can effectively reduce the macrophage uptake in vitro , prolong the circulation half-life in vivo and decrease the accumulation ...Author: Ting Zhang, Zhennan She, Zhenjun Huang, Jing Li, Xiang Luo, Yihui Deng
https://www.sciencedirect.com/science/article/pii/0014579393811772
A number of bacterial polysialic acids were injected intravenously into mice. Half-lives (up to 40 h) in the blood circulation were dependent on the polysialic acid used, increased by deacylation of their phospholipid moiety, decreased with shorter chain derivatives and appeared to be dose independent.Author: G. Gregoriadis, B. McCormack, Z. Wang, R. Lifely
https://www.ncbi.nlm.nih.gov/pubmed/8422917
Jan 11, 1993 · Half-lives (up to 40 h) in the blood circulation were dependent on the polysialic acid used, increased by deacylation of their phospholipid moiety, decreased with shorter chain derivatives and appeared to be dose independent. A model drug (fluorescein) covalently coupled to a polysialic acid was found to assume the half-life of its carrier.Author: G. Gregoriadis, B. McCormack, Z. Wang, R. Lifely
https://www.future-science.com/doi/full/10.4155/tde.13.153
14 Greco F, Arif I, Botting R et al. Polysialic acid as a drug carrier: evaluation of a new polysialic acid-epirubicin conjugate and its comparison against established drug carriers. Polym. Chem. 4(5),1600–1609 (2013).Crossref, CAS, Google Scholar; 15 Moghimi SM, Hunter AC, Murray JC. Long-circulating and target-specific nanoparticles: theory ...Author: Rebecca A Bader, Patricia R Wardwell
https://surface.syr.edu/cgi/viewcontent.cgi?article=1907&context=honors_capstone
within the body by drug delivery systems can be used to accomplish such objectives. This project aims to evaluate a method to increase drug efficacy while ... time and decreased degradation by shielding the encapsulated drug. Polysialic acid (PSA) is a hydrophilic saccharide polymer that has ben previously shown to work well as part of a ...Author: Weston Ryan
https://www.ncbi.nlm.nih.gov/pubmed/29536348
Polysialic acid (PSA) is a nonimmunogenic and biodegradable polysaccharide. In recent years, PSA has shown its potential applications to cancer treatment. In this study, PSA-polyethylene glycol (PEG) conjugate was synthesized for the decoration of epirubicin (EPI)-loaded liposomes.Author: Ting Zhang, Songlei Zhou, Ling Hu, Bo Peng, Yang Liu, Xiang Luo, Xinrong Liu, Yanzhi Song, Yihui Den...
https://experts.syr.edu/en/publications/polysialic-acid-polycaprolactone-micelles-for-drug-delivery
TY - PAT. T1 - Polysialic Acid-Polycaprolactone Micelles for Drug Delivery. AU - Bader, Rebecca. PY - 2018/7/17. Y1 - 2018/7/17. N2 - PSA-PCL micelles were developed as …Author: Rebecca Bader
https://www.researchgate.net/publication/262881230_Application_of_sialic_acidpolysialic_acid_in_the_drug_delivery_systems
The properties of modified biomaterial are gaining more and more importance in drug delivery systems. Sialic acid (SA) and polysialic acid (PSA) serve as endogenous substances, which are non ...
https://patents.google.com/patent/US10022324B2/en
PSA-PCL micelles were developed as carrier systems for pharmaceutical drugs. As an example, cyclosporine A (CyA) was encapsulated in the micelles and physical characterization, including size and zeta potential, demonstrated that the micelles possess favorable properties for drug delivery. In vitro studies verified that rheumatoid arthritis synovial fibroblasts are able to internalize the CyA ...Author: Rebecca Bader
https://www.xeneticbio.com/technology/polyxen
PolyXen for Protein Drug Delivery. PolyXen is an enabling platform technology for protein and peptide drug delivery. It uses the biological polymer polysialic acid (PSA) to prolong the drug's half-life and potentially improve the stability of therapeutic peptides and proteins.
Searching for Polysialic Acid Drug Delivery?
You can just click the links above. The data is collected for you.
