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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255357/
The application of mucoadhesive polymers in nasal drug delivery systems has gained to promote dosage form residence time in the nasal cavity as well as improving intimacy of contact with absorptive membranes of the biological system. The various new technology uses in development of nasal drug delivery dosage forms are discussed.
https://www.tandfonline.com/doi/abs/10.1163/138577209X12478283327236
Oct 14, 2004 · The substrate possessing bioadhesive property can help in devising a delivery system capable of delivering a bioactive agent for a prolonged period of time at a specific delivery site. The current review provides a good insight on mucoadhesive polymers, the phenomenon of mucoadhesion and the factors which have the ability to affect the mucoadhesive properties of a polymer.Author: S. Roy, K. Pal, A. Anis, K. Pramanik, B. Prabhakar
https://www.tandfonline.com/doi/abs/10.1080/03639040802026012
Oct 20, 2008 · Bioadhesive polymers find application in the eye, nose, and vaginal cavity as well as in the GI tract, including the buccal cavity and rectum. This article lays emphasis mainly on mucoadhesive polymers, their properties, and their applications in buccal, ocular, nasal, and vaginal drug delivery systems with its evaluation methods.Author: G. S. Asane, S. A. Nirmal, K. B. Rasal, A. A. Naik, M. S. Mahadik, Y. Madhusudan Rao
https://www.researchgate.net/publication/23187120_Polymers_for_Mucoadhesive_Drug_Delivery_System_A_Current_Status
The main components of bioadhesive drug delivery systems are bioadhesive polymers, which may be natural or synthetic in nature. The success of bioadhesive drug delivery systems depends upon...
https://www.mdpi.com/journal/polymers/special_issues/drug-delivery
A mucoadhesive drug delivery system can improve the effectiveness of a drug by maintaining the drug concentration and allowing targeting and localization of the drug at a specific site. Acrylic-based hydrogels have been used extensively as a mucoadhesive system owing to their flexibility and excellent bioadhesion.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
This makes the buccal cavity more suitable for mucoadhesive drug delivery. The various mucoadhesive polymers used for the development of buccal delivery systems include cyanoacrylates, polyacrylic acid, sodium carboxymethylcellulose, hyaluronic acid, hydroxypropylcellulose, polycarbophil, chitosan and gellan.
https://www.sciencedirect.com/science/article/pii/S1381514816300104
Gastroretentive mucoadhesive tablets made up of xanthan gum, sodium alginate and karaya gum were evaluated for controlled delivery and improved bioavailability of lafutidine. Out of these three natural polymers the gastroretentive tablets consist of xanthan gum showed better results in terms of percent drug release…Author: Shakir Mansuri, Prashant Kesharwani, Prashant Kesharwani, Keerti Jain, Rakesh K. Tekade, N.K. Jain
https://www.sciencedirect.com/science/article/pii/S0169409X00001204/
One of the most promising strategies for designing mucoadhesive particulate systems is surface modification, or coating, of the drug carrier particles with mucoadhesive polymers. For coarse particles, a conventional coating method, such as fluidized bed coating, can be used.Author: Hirofumi Takeuchi, Hiromitsu Yamamoto, Yoshiaki Kawashima
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