Polymeric Nanoparticles Sirna Delivery Gene Silencing

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Polymeric nanoparticles for siRNA delivery and gene silencing.

    https://www.ncbi.nlm.nih.gov/pubmed/18940242
    Feb 09, 2009 · Polymeric nanoparticles for siRNA delivery and gene silencing. Patil Y(1), Panyam J. Author information: (1)Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.Author: Yogesh Patil, Yogesh Patil, Jayanth Panyam

Polymeric nanoparticles for siRNA delivery and gene ...

    https://www.sciencedirect.com/science/article/pii/S0378517308006704
    Gene silencing using small interfering RNA (siRNA) has several potential therapeutic applications. In the present study, we investigated nanoparticles formulated using the biodegradable polymer, poly(d, l-lactide-co-glycolide) (PLGA) for siRNA delivery.A cationic polymer, polyethylenimine (PEI), was incorporated in the PLGA matrix to improve siRNA encapsulation in PLGA nanoparticles.Author: Yogesh Patil, Yogesh Patil, Jayanth Panyam

Polymeric Nanoparticles for siRNA Delivery and Gene Silencing

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660441/
    Feb 09, 2009 · Gene silencing using small interfering RNA (siRNA) has several potential therapeutic applications. In the present study, we investigated nanoparticles formulated using the biodegradable polymer, poly(d, l-lactide-co-glycolide) (PLGA) for siRNA delivery.A cationic polymer, polyethylenimine (PEI), was incorporated in the PLGA matrix to improve siRNA encapsulation in PLGA nanoparticles.Author: Yogesh Patil, Yogesh Patil, Jayanth Panyam

Polymeric Nanoparticles for siRNA Delivery and Gene ...

    https://www.researchgate.net/publication/23402893_Polymeric_Nanoparticles_for_siRNA_Delivery_and_Gene_Silencing
    Polymeric Nanoparticles for siRNA Delivery and Gene Silencing Article in International Journal of Pharmaceutics 367(1-2):195-203 · November 2008 with 152 Reads How we measure 'reads'

Polymeric nanoparticles for siRNA delivery: Production and ...

    https://www.sciencedirect.com/science/article/pii/S0378517317302880
    1. Introduction. In these last two decades, short interfering ribonucleic acids (siRNA) gained much attention thanks to their highly efficient role in the post-transcriptional gene silencing in most eukaryotic cells (Cooper and Putnam, 2016, Sarett et al., 2015).From the first discovery in 1998 by Fire and Mello (the 2006 Nobel prizes for their discovery of RNA interference and gene silencing ...Author: Gennara Cavallaro, Carla Sardo, Emanuela Fabiola Craparo, Barbara Porsio, Gaetano Giammona

Polymeric nanoparticles for siRNA delivery and gene ...

    https://experts.umn.edu/en/publications/polymeric-nanoparticles-for-sirna-delivery-and-gene-silencing
    Gene silencing using small interfering RNA (siRNA) has several potential therapeutic applications. In the present study, we investigated nanoparticles formulated using the biodegradable polymer, poly(d,l-lactide-co-glycolide) (PLGA) for siRNA delivery.Author: Yogesh Patil, Yogesh Patil, Jayanth Panyam

Polymeric nanoparticles for siRNA delivery and gene ...

    https://www.deepdyve.com/lp/elsevier/polymeric-nanoparticles-for-sirna-delivery-and-gene-silencing-YUrhCbfbOE
    Feb 09, 2009 · Read "Polymeric nanoparticles for siRNA delivery and gene silencing, International Journal of Pharmaceutics" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

Reductively Responsive siRNA-Conjugated Hydrogel ...

    https://pubs.acs.org/doi/10.1021/ja300174v
    Gene silencing efficiency and cytocompatibility were optimized by screening the amine content of the particles. When appropriate control siRNA cargos were loaded into hydrogels, gene knockdown was only encountered for hydrogels containing releasable, target-specific siRNAs, accompanied by …Author: Stuart S. Dunn, Shaomin Tian, Steven Blake, Jin Wang, Ashley L. Galloway, Andrew Murphy, Patrick D. ...

Gene Silencing by siRNA Microhydrogels via Polymeric ...

    https://pubs.acs.org/doi/10.1021/ja2056984
    The siRNA microhydrogels were condensed using a popular cationic polymer such as LPEI to form compact, stable siRNA/polymeric nanoparticles that exhibited …Author: Cheol Am Hong, Soo Hyeon Lee, Jee Seon Kim, Ji Won Park, Ki Hyun Bae, Hyejung Mok, Tae Gwan Park, Ha...

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