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https://www.researchgate.net/publication/233410257_Polymer_nanoparticulate_drug_delivery_and_combination_cancer_therapy
Polymer nanoparticulate drug delivery and combination cancer therapy Article · Literature Review in Future Oncology 8(11):1471-1480 · November 2012 with 27 Reads How we measure 'reads'
https://www.sciencedirect.com/science/article/pii/S1359644612001870
Nanotechnology has been developed as a powerful tool for cancer drug delivery. Here, we have discussed the current status of combination drug delivery based nanocarriers as an emerging approach for cancer therapy, as well as the need to develop such …Author: Priyambada Parhi, Chandana Mohanty, Sanjeeb Kumar Sahoo
https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.22886
Aug 14, 2007 · Ovarian cancer treatment is associated with high degree of relapse due to acquisition of drug resistant phenotype. In this study, we have investigated the potential for specific delivery of combination PTX and CER therapy to overcome drug resistance in ovarian cancer.Author: Harikrishna Devalapally, Zhenfeng Duan, Michael V. Seiden, Mansoor M. Amiji
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377179/
Mar 21, 2015 · Cancer therapy based on single drug remains unsatisfying due to the complex microenvironment of cancer cells along with the drug resistance mechanisms. . In this regard, combination therapy has been considered as a promising strategy to improve therapeutic efficiency and to minimize side effects.Author: Bing Wang, Xiu-Chun Yu, Song-Feng Xu, Ming Xu
https://pubs.acs.org/doi/abs/10.1021/nn4010796
The combination of a chemotherapeutic drug with a multidrug resistance (MDR) modulator has emerged as a promising strategy for treating MDR cancer. To ensure two drugs could be simultaneously delivered to tumor region at the optimum ratio, and the MDR modulator could be released earlier and faster than the chemotherapeutic drug to inactivate P-glycoprotein (P-gp) and subsequently inhibit the ...Author: Xiaopin Duan, Jisheng Xiao, Qi Yin, Zhiwen Zhang, Haijun Yu, Shirui Mao, Yaping Li
https://www.sciencedirect.com/science/article/pii/S0006295212000330
1. Introduction. The long-standing challenge in cancer drug resistance and the urgent need for novel combination therapy are highlighted in a recent perspective by Woodcock et al., who liken the complexity of cancer biology to webs of interconnected routes with multiple redundancies .Very tellingly, this analogy points out the inadequacy of single-drug therapy, whose one-dimensional action ...Author: Che-Ming Jack Hu, Liangfang Zhang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980181/
Nanoparticles Containing Insoluble Drug for Cancer Therapy. ... (Bangham and Horne, 1964), liposomes formed from amphiphilic phospholipids and cholesterol became one of the first nanoparticulate platforms for drug delivery. When the lipid film is hydrated, the hydrophobic drugs can be successfully incorporated in a bilayer of liposomes ...
https://aiche.onlinelibrary.wiley.com/doi/pdf/10.1002/btm2.10033
their parent drugs. Polymeric drug delivery NPs, one of the major deliv-ery platforms, has actively evolved its paradigm from water-soluble polymeric carriers, to liposome, micelle, dendrimer, polymersome, and other polymeric nanostructures.17–19 1.2 The development of the PDC PDC is one of the most important and oldest polymeric deliveryAuthor: Quanyou Feng, Rong Tong
https://pubs.acs.org/doi/10.1021/mp200243k
Jun 22, 2011 · Preparation of dual-drug conjugated polymeric micelles with synergistic anti-cancer efficacy in vitro. ... Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come. ... Polymer nanoparticulate drug delivery and combination cancer therapy. Future Oncology 2012, 8 (11) , 1471-1480. DOI: 10.2217/fon.12.139. ...Author: Santosh Aryal, Che Ming Jack Hu, Liangfang Zhang
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