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http://old.iupac.org/publications/pac/2004/pdf/7607x1321.pdf
livery systems, polymeric micelles represent a promising delivery vehicle especially intended for poorly water-soluble pharmaceutical active ingredients in order to improve their oral bioavailability.
https://www.researchgate.net/publication/228781219_Polymeric_Micelles_for_Oral_Drug_Delivery_Why_and_How
Polymeric Micelles for Oral Drug Delivery: Why and How Article (PDF Available) in Pure and Applied Chemistry 76(7):1321-1335 · July 2004 with 272 Reads How we measure 'reads'
https://www.degruyter.com/view/j/pac.2004.76.issue-7-8/pac200476071321/pac200476071321.xml
Jan 01, 2004 · Many approaches to achieve the oral absorption of a wide variety of drugs are currently under investigation. Among the different polymer-based drug delivery systems, polymeric micelles represent a promising delivery vehicle especially intended for poorly water-soluble pharmaceutical active ingredients in order to improve their oral bioavailability.Author: Mira F. Francis, Mariana Cristea, Francoise M. Winnik
https://www.sciencedirect.com/science/article/pii/S0939641110001566
Polymeric micelles, which form upon self-assembly of amphiphilic macromolecules, can act as vehicles for the oral delivery of these drugs. This manuscript summarizes the literature in relation to the design of these micellar systems and their characterization with respect to drug loading and retention properties as well as the ability to withstand dissociation and drug discharge upon oral administration.Author: Geneviève Gaucher, Prashant Satturwar, Marie-Christine Jones, Alexandra Furtos, Jean-Christophe Lero...
https://www.ncbi.nlm.nih.gov/pubmed/20600891
Polymeric micelles, which form upon self-assembly of amphiphilic macromolecules, can act as vehicles for the oral delivery of these drugs. This manuscript summarizes the literature in relation to the design of these micellar systems and their characterization with respect to drug loading and retention properties as well as the ability to withstand dissociation and drug discharge upon oral administration.Author: Geneviève Gaucher, Prashant Satturwar, Marie-Christine Jones, Alexandra Furtos, Jean-Christophe Lero...
https://www.sciencedirect.com/science/article/abs/pii/S0939641110001566
Polymeric micelles, which form upon self-assembly of amphiphilic macromolecules, can act as vehicles for the oral delivery of these drugs. This manuscript summarizes the literature in relation to the design of these micellar systems and their characterization with respect to drug loading and retention properties as well as the ability to withstand dissociation and drug discharge upon oral administration.Author: Geneviève Gaucher, Prashant Satturwar, Marie-Christine Jones, Alexandra Furtos, Jean-Christophe Lero...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712247/
Jun 27, 2013 · Polymeric micelles (PMs) can overcome some limitations of the oral delivery acting as carriers able to enhance drug absorption, by providing (1) protection of the loaded drug from the harsh environment of the GI tract, (2) release of the drug in a controlled manner at target sites, (3) prolongation of the residence time in the gut by mucoadhesion, and (4) inhibition of efflux pumps to improve the …Author: Wei Xu, Peixue Ling, Tianmin Zhang
https://www.ncbi.nlm.nih.gov/pubmed/17168771
Both the inherent and modifiable properties of polymeric micelles make them particularly well suited for drug delivery purposes. An emphasis of this review has been placed on both the description and characterization techniques of the physical properties of polymeric micelles.Author: S. R. Croy, G. S. Kwon
https://www.sciencedirect.com/topics/materials-science/micelle
Polymeric micelles have attracted much attention in drug delivery because of their ability to solubilize hydrophobic molecules, their small particle size, good thermodynamic solution stability, extended release of various drugs, and prevention of rapid clearance by the reticuloendothelial system (RES). Low critical micelle concentration (CMC), is another key characterization parameter for polymeric …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801582/
POLYMERIC MICELLES IN SKIN DRUG DELIVERY. Polymeric micelles have been investigated as alternative vehicles for parenteral, oral, ocular, pulmonary, and nasal routes. However, investigation to targeted cutaneous delivery by application of polymeric micelles is rare, and the mechanism of their action is not clearly demonstrated.
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