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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309804/
Dec 11, 2014 · In concurrent drug delivery, polymeric micelles deliver multi-poorly water-soluble anticancer agents, satisfying strict requirements in solubility, stability, and safety. In sequential drug delivery, polymeric micelles participate in pretreatment strategies that “prime” solid tumors and enhance the penetration of secondarily administered anticancer agent or nanocarrier.Author: Hyunah Cho, Hyunah Cho, Tsz Chung Lai, Keishiro Tomoda, Glen S. Kwon, Glen S. Kwon
https://www.ncbi.nlm.nih.gov/pubmed/25501872
In concurrent drug delivery, polymeric micelles deliver multi-poorly water-soluble anticancer agents, satisfying strict requirements in solubility, stability, and safety. In sequential drug delivery, polymeric micelles participate in pretreatment strategies that "prime" solid tumors and enhance the penetration of secondarily administered anticancer agent or nanocarrier.Author: Hyunah Cho, Hyunah Cho, Tsz Chung Lai, Keishiro Tomoda, Glen S. Kwon, Glen S. Kwon
https://link.springer.com/article/10.1208%2Fs12249-014-0251-3
Dec 11, 2014 · In this contribution, we review recent research on polymeric micelles for multi-drug delivery in cancer. In concurrent drug delivery, polymeric micelles deliver multi-poorly water-soluble anticancer agents, satisfying strict requirements in solubility, stability, and safety.Author: Hyunah Cho, Hyunah Cho, Tsz Chung Lai, Keishiro Tomoda, Glen S. Kwon, Glen S. Kwon
https://www.researchgate.net/publication/269717215_Polymeric_Micelles_for_Multi-Drug_Delivery_in_Cancer
In concurrent drug delivery, polymeric micelles deliver multi-poorly water-soluble anticancer agents, satisfying strict requirements in solubility, stability, and safety.
https://www.sciencedirect.com/science/article/pii/S0928098715301056
Therefore, advantages of polymeric micelles as drug delivery carriers in cancer therapy include their potential to solubilize the pharmaceutical components of poor aqueous solubility into the hydrophobic core, improve the pharmacokinetic properties and biodistribution, and specifically target their payload to the tumor tissues by tuning their ...Author: Swati Biswas, Preeti Kumari, Prit Manish Lakhani, Balaram Ghosh
https://pubs.acs.org/doi/abs/10.1021/nl061412u
We describe the development of multifunctional polymeric micelles with cancer-targeting capability via α v β 3 integrins, controlled drug delivery, and efficient magnetic resonance imaging (MRI) contrast characteristics. Doxorubicin and a cluster of superparamagnetic iron oxide (SPIO) nanoparticles were loaded successfully inside the micelle core.Author: Norased Nasongkla, Erik Bey, Jimin Ren, Hua Ai, Chalermchai Khemtong, Jagadeesh Setti Guthi, Shook F...
https://www.sciencedirect.com/science/article/pii/B9780128097175000063
Block copolymer micelles are one of the most promising classes of nanoparticles used in drug delivery. Block copolymers are formed by one homopolymer attached to one or more other homopolymers. These blocks are repeated throughout the structure of the copolymer …Author: Mohd Cairul Iqbal Mohd Amin, Adeel M. Butt, Muhammad W. Amjad, Prashant Kesharwani
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787857/
Dec 16, 2009 · For all SDMs and MDMs approximately100% of the initial amount of the drug (s) and polymer was recovered as loaded PEG- b -PLA micelles. The capacity of these PEG- b -PLA micelles to incorporate drugs increased as the number drugs being loaded increased.Author: Ho-Chul Shin, Adam W.G. Alani, Deepa A. Rao, Nicole C. Rockich, Glen S. Kwon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982955/
Aug 20, 2010 · Polymeric micelles are based on block-copolymers with hydrophilic and hydrophobic units that self-assemble in an aqueous environment into structures composed of a hydrophobic core stabilized by a hydrophilic shell. These blocks can be arranged in different ways: A-B type copolymers (diblock copolymer),...Author: Chris Oerlemans, Wouter Bult, Mariska Bos, Gert Storm, J. Frank W. Nijsen, Wim E. Hennink
https://pubs.rsc.org/en/content/articlelanding/2017/py/c7py01675a
Reduction-responsive dithiomaleimide-based polymeric micelles for controlled anti-cancer drug delivery and bioimaging† Ting Bai , a Junjie Du , a Jianxin Chen , a Xiao Duan , a Qiang Zhuang , a Heng Chen a and Jie Kong * aAuthor: Ting Bai, Junjie Du, Jianxin Chen, Xiao Duan, Qiang Zhuang, Heng Chen, Jie Kong
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