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https://www.tandfonline.com/doi/pdf/10.3109/10717541003762854
This review will explore biodegradable polymeric drug delivery systems pre-clinically investigated for localized chemotherapy that have shown anti-tumor promise in animal models of cancer. We have chosen to focus on delivery systems for chemotherapeutics only; thus, sys-tems designed to deliver biologics will not be discussed. This review ...
https://www.researchgate.net/publication/43353803_Polymeric_drug_delivery_systems_for_localized_cancer_chemotherapy
Polymeric drug delivery systems for localized cancer chemotherapy Article · Literature Review in Drug Delivery 17(6):365-75 · August 2010 with 100 Reads How we measure 'reads'
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374380/
Mar 13, 2012 · The further development of dendrimers as multifunctional drug delivery systems functionalized with drugs, targeting moieties, and imaging agents have been the subject of several recent reviews 97, 119, 120. Several studies have also compared dendritic carriers to other more traditional polymeric carriers such as HPMA copolymers and PEG.Author: Nate Larson, Hamidreza Ghandehari
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
Modern advances in drug delivery are now predicated upon the rational design of polymers tailored for specific cargo and engineered to exert distinct biological functions. In this review, we highlight the fundamental drug delivery systems and their mathematical foundations and discuss the physiological barriers to drug delivery.Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · Novel drug delivery systems promise a bright future for cancer treatment in the next decade or so; they might become major arsenal for safer …Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti
https://www.drugdiscoverytrends.com/localized-drug-delivery-promises-to-improve-outcomes-and-reduce-side-effects/
Jun 26, 2018 · The development of a successful strategy for localized drug delivery requires an understanding of the transport of drugs or drug carriers to a target site after administration, as well as issues relevant to disease-specific targets and the body’s response to a drug delivery system.
http://europepmc.org/abstract/MED/20429844
Sep 01, 2010 · Polymers have been widely considered in the development of localized delivery systems. This review focuses on both natural and synthetic biodegradable polymers that have been explored for localized chemotherapy, exploring their advantages, disadvantages, and clinical potential while citing examples of their use in pre-clinical development.Author: Raquel De Souza, Payam Zahedi, Christine J. Allen, Micheline Piquette-Miller
https://www.researchgate.net/publication/295261762_Drug_Delivery_Systems_Based_on_Polymeric_Micelles_and_Ultrasound_A_Review
Drug Delivery Systems Based on Polymeric Micelles and Ultrasound: A Review ... in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles reduces the adverse side ...
https://www.sciencedirect.com/science/article/pii/S0169409X97000367
Cancer chemotherapy is not always effective. Difficulties in drug delivery to the tumor, drug toxicity to normal tissues, and drug stability in the body contribute to this problem. Polymeric materials provide an alternate means for delivering chemotherapeutic agents.Author: Lawrence K. Fung, W.Mark Saltzman
https://www.sciencedirect.com/science/article/pii/B9780128136652000132
The concept of implantable drug delivery systems (IDDSs) in modern medicine may be traced to Deansby and Parkes who, in 1938, subcutaneously (SC) implanted compressed pellets of crystalline estrone to study their effect upon castrated male chickens (Kleiner et al., 2014).Folkman and Long pioneered implantable formulations, with drug release rates controlled by a polymeric membrane, in the 1960s.Author: Anoop Kumar, Jonathan Pillai
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