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https://www.tandfonline.com/doi/pdf/10.3109/10717541003762854
This review will explore biodegradable polymeric drug delivery systems pre-clinically investigated for localized chemotherapy that have shown anti-tumor promise in animal models of cancer. We have chosen to focus on delivery systems for chemotherapeutics only; thus, sys-tems designed to deliver biologics will not be discussed. This review ...
https://www.researchgate.net/publication/43353803_Polymeric_drug_delivery_systems_for_localized_cancer_chemotherapy
Request PDF Polymeric drug delivery systems for localized cancer chemotherapy Cancer has become one of the most difficult health challenges of our time, accounting for millions of deaths yearly.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471357/
Mar 15, 2019 · In this review, we have discussed the different types of block co-polymers that have been formulated into polymeric co-delivery systems for cancer treatment. We also focused on the different drug combinations used in co-delivery systems and the influence …Author: Jiayi Pan, Kobra Rostamizadeh, Nina Filipczak, Vladimir P. Torchilin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878823/
Apr 10, 2012 · 1. Introduction. Polymer-based drug delivery systems have been investigated over the last few decades as a means of achieving high therapeutic concentrations of chemotherapy to the site of malignant disease in cancer patients[1-10].The development of these technologies is guided by the desire to improve overall survival and quality of life by increasing the bioavailability of drug to the site ...Author: Jesse B. Wolinsky, Yolonda L. Colson, Mark W. Grinstaff
https://www.researchgate.net/publication/307589790_Polymer-Based_Drug_Delivery_Systems_for_Cancer_Treatment
This review is focused on the chemical design and synthesis of polymer-based drug delivery systems, in particular with stimuli-responsive nanoplatforms for cancer treatment.
http://www.rroij.com/open-access/novel-delivery-systems-in-cancer-chemotherapy.php?aid=34825
In this article, we review some of the drug-delivery systems that are FDA-approved and in clinical use against a variety of cancers. These systems include controlled delivery of cancer drugs, local chemotherapy, polymer-drug conjugates, liposomal systems and trans dermal drug-delivery patches.Author: N Rathna Prasanna, C Triveni, R Soumya, BV Ramana, G Nagarajan
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · Future challenges in cancer therapy. Novel drug delivery systems promise a bright future for cancer treatment in the next decade or so; they might become major arsenal for …Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti
http://europepmc.org/abstract/MED/20429844
Sep 01, 2010 · Cancer has become one of the most difficult health challenges of our time, accounting for millions of deaths yearly. Systemic chemotherapy is the most common therapeutic approach; however, considerable limitations exist including toxicities to healthy tissues and low achievable drug concentrations at tumor sites.Author: Raquel De Souza, Payam Zahedi, Christine J. Allen, Micheline Piquette-Miller
https://www.tandfonline.com/doi/full/10.3109/10717541003762854
Jul 21, 2014 · Many polymeric delivery systems for localized chemotherapy fail to reach the market as results obtained pre-clinically often do not translate successfully in clinical development. An example is Paclimer ®, polyphosphoester microspheres for localized delivery of paclitaxel.Author: Raquel De Souza, Payam Zahedi, Christine J. Allen, Micheline Piquette-Miller
https://www.drugdiscoverytrends.com/localized-drug-delivery-promises-to-improve-outcomes-and-reduce-side-effects/
Jun 26, 2018 · The development of a successful strategy for localized drug delivery requires an understanding of the transport of drugs or drug carriers to a target site after administration, as well as issues relevant to disease-specific targets and the body’s response to a drug delivery system.
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