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https://www.onlinelibrary.wiley.com/doi/10.1002/9781118444726.ch5
Jan 21, 2013 · This review is based on drug delivery systems involving hydrophobic drug encapsulation. It explains the different methods of preparation for polymeric nanoparticles containing hydrophobic drugs with biocompatibility profiles of polymers.Author: Naveed Ahmed, C.E. Mora‐Huertas, Chiraz Jaafar‐Maalej, Hatem Fessi, Abdelhamid Elaissari
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
Polymers have played an integral role in the advancement of drug delivery technology by providing controlled release of therapeutic agents in constant doses over long periods, cyclic dosage, and tunable release of both hydrophilic and hydrophobic drugs.Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.researchgate.net/publication/295261762_Drug_Delivery_Systems_Based_on_Polymeric_Micelles_and_Ultrasound_A_Review
Drug Delivery Systems Based on Polymeric Micelles and Ultrasound: A Review ... as nanocarriers for hydrophobic drugs. They can be designed to have increased stability and blood circulation time ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471357/
Mar 15, 2019 · The hydrophobic delivery systems containing PCT are based on the entrapment of the drug in their hydrophobic core. The combination of DOX and PCT in mPEG-PLGA polymeric nanoparticles made by a dual emulsion method has allowed a better anti-cancer effect in vivo and a much faster release of the drug from the carrier in an acidic environment [ 79 ].Author: Jiayi Pan, Kobra Rostamizadeh, Nina Filipczak, Vladimir P. Torchilin
https://www.sciencedirect.com/science/article/pii/S2211383515001069
Liposomes have been regarded as new drug delivery systems capable of transporting drug molecules to specific target site with enhanced efficacy and safety 92. A potential advantage of liposomes is the encapsulation of hydrophobic as well as hydrophilic drugs, either in the phospholipid bilayer, at the bilayer interface or in the entrapped ...Author: Sandeep Kalepu, Vijaykumar Nekkanti
https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/Method/1/polymeric-drug-delivery-techniques-web.pdf
otherwise promising therapeutic candidate. Drug delivery systems can be formulated to improve the in vivo solubility of lipophilic and hydrophobic drugs by encapsulation in a drug delivery carrier or by conjugation with a polymer. Selecting a Polymeric Drug Delivery System There are three main categories of polymeric drug delivery systems;
https://www.sciencedirect.com/science/article/pii/B9780128097175000063
Polymeric micelles (PMs) have been extensively explored in order to facilitate the delivery of hydrophobic drugs. PMs are spontaneously formed from amphiphilic copolymers in aqueous media, when the critical micelle concentration (CMC) is achieved, as shown in Fig. 5.1.The differences between the solubility of the hydrophilic and hydrophobic blocks of an amphiphilic copolymer in an aqueous ...Author: Mohd Cairul Iqbal Mohd Amin, Adeel M. Butt, Muhammad W. Amjad, Prashant Kesharwani
https://www.researchgate.net/publication/277691548_Drug_Delivery_Strategies_for_Poorly_Water-Soluble_Drugs
The second chapter on polymeric drug delivery systems focuses on techniques that produce particles by in situ polymerization of monomers. It provides a description of the preparation techniques ...Author: Dagmar Fischer
https://www.wiley.com/en-us/Drug+Delivery+Strategies+for+Poorly+Water+Soluble+Drugs-p-9781118444672
Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, self–microemulsifying drug delivery systems ...
https://www.hindawi.com/journals/jdd/2013/340315/
Oral administration is the most commonly used and readily accepted form of drug delivery; however, it is find that many drugs are difficult to attain enough bioavailability when administered via this route. Polymeric micelles (PMs) can overcome some limitations of the oral delivery acting as carriers able to enhance drug absorption, by providing (1) protection of the loaded drug from the harsh ...Author: Wei Xu, Peixue Ling, Tianmin Zhang
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