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https://www.sciencedirect.com/science/article/pii/S0169409X02000509
Masters et al. have used a polyanhydride cylinder for the delivery of local anesthetics in close proximity to the sciatic nerve to produce a neuronal block for several days , . The use of polyanhydrides in oral delivery of insulin and plasmid DNA has been investigated .Author: Neeraj Kumar, Robert S Langer, Abraham J Domb
https://www.sciencedirect.com/topics/chemistry/polyanhydride
A comprehensive evaluation of the toxicity of the polyanhydrides showed that, in general, they possess excellent in vivo biocompatibility [172].Their most immediate applications are in the field of drug delivery, although tissue-engineering applications are also being developed.
https://www.ncbi.nlm.nih.gov/pubmed/1350734
One section is devoted to a case study to provide a historical perspective of the development a polyanhydride-based drug delivery treatment from the conception of the idea to the final stages of human clinical trials. This section includes an outline of the extensive in vitro and in vivo testing that is necessary for development of a new ...Author: J. Tamada, R. Langer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565095/
Drug delivery is a field of vital importance to medicine and healthcare. Controlled drug delivery improves bioavailability by preventing premature degradation and enhancing uptake, maintains drug concentration within the therapeutic window by controlling the drug release rate, and reduces side effects by targeting to disease site and target cells.Author: Ying Zhang, Hon Fai Chan, Kam W. Leong
https://rucore.libraries.rutgers.edu/rutgers-lib/24400/PDF/1/play/
Polyanhydride Blends for Drug Delivery, Biofilm Prevention, and Tissue Engineering By MICHELLE LINETTE JOHNSON Dissertation Director: Kathryn E. Uhrich Biodegradable polyanhydrides were fabricated into disks, coatings, microspheres, and tubes for controlled drug delivery as well as enhanced thermal and mechanical properties.
https://www.pharmatutor.org/articles/polyanhydride-microspheres-controlled-drug-delivery-lung
Various biodegradable polymers have been prepared for controlled of antihypertensive agents (Diltiazem) [3], controlled drug delivery of chemotherapy [4] and protein loaded polyanhydride micospheres for controlled delivery [5],[6]. The goal has been to develop implantable or injectable devices that provide controlled release of the drug for a ...
https://www.tandfonline.com/doi/abs/10.1163/156856292X00402
Aug 19, 2008 · One section is devoted to a case study to provide a historical perspective of the development a polyanhydride-based drug delivery treatment from the conception of the idea to the final stages of human clinical trials.Author: J. Tamada, R. Langer
https://www.researchgate.net/publication/307589790_Polymer-Based_Drug_Delivery_Systems_for_Cancer_Treatment
This review is focused on the chemical design and synthesis of polymer-based drug delivery systems, in particular with stimuli-responsive nanoplatforms for cancer treatment.
https://www.researchgate.net/publication/23180283_Polyanhydrides_as_localized_drug_delivery_carrier_An_update
To demonstrate the advantages of localized delivery using basic concepts and describing polyanhydride carrier with products such as Gliadel and Septacin. ... Polyanhydrides as localized drug ...
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