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https://www.sciencedirect.com/science/article/pii/0142961283900546
Bioerodible polyanhydrides for controlled drug delivery H. B. Rosei^, J. Chang^, G. E. Wirf, R. J. Lmhardt04 and R. Langer0-' "Dept, of Chemical Engineering, ''Dept. of Materials Science and Engineering, "Dept. of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; ''Division of Medicinal Chemistry, College of Pharmacy, University of Iowa, Iowa City ...Author: Robert S. Langer, Howard Rosen
https://www.ncbi.nlm.nih.gov/pubmed/6860755
1. Biomaterials. 1983 Apr;4(2):131-3. Bioerodible polyanhydrides for controlled drug delivery. Rosen HB, Chang J, Wnek GE, Linhardt RJ, Langer R.Author: Robert S. Langer, Howard Rosen
https://www.sciencedirect.com/topics/medicine-and-dentistry/polyanhydrides
A comprehensive evaluation of the toxicity of the polyanhydrides showed that, in general, they possess excellent in vivo biocompatibility [172]. Their most immediate applications are in the field of drug delivery, although tissue-engineering applications are also being developed.
https://www.gsb.stanford.edu/faculty-research/publications/bioerodible-polyanhydrides-controlled-drug-delivery
Bioerodible polyanhydrides for controlled drug delivery. Bioerodible polyanhydrides for controlled drug delivery. By. Howie Rosen, J. Chang, G.E. Wnek, R.J. Linhardt, R. Langer. ... poly[bis(p-carboxyphenoxy)methane], as a bioerodible matrix for controlled drug delivery are described. Drug delivery matrices fabricated from this material and ...
https://polymerdatabase.com/polymer%20classes/Polyanhydride%20type.html
The anhydrides are highly susceptible to hydrolysis and degrade into non-toxic diacid monomers that can be metabolized and eliminated from the body, that is, many polyanhydrides are considered to be biocompatible. This property makes this class of polymers suitable as biodegradable controlled-release coatings for drug delivery systems.
https://www.mddionline.com/polymers-controlled-drug-delivery
Polyanhydrides. Polyorthoesters. Originally, polylactides and polyglycolides were used as absorbable suture material, and it was a natural step to work with these polymers in controlled drug delivery systems. The greatest advantage of these degradable polymers is that they are broken down into biologically acceptable molecules that are ...
https://www.pharmatutor.org/articles/polyanhydride-microspheres-controlled-drug-delivery-lung
Various biodegradable polymers have been prepared for controlled of antihypertensive agents (Diltiazem) [3], controlled drug delivery of chemotherapy [4] and protein loaded polyanhydride micospheres for controlled delivery [5],[6]. The goal has been to develop implantable or injectable devices that provide controlled release of the drug for a ...
https://www.researchgate.net/publication/225729572_Polyanhydrides_Synthesis_and_characterization
Polyanhydrides are useful bioabsorbable materials for controlled drug delivery. They are hydrolytically unstable and hydrolyze to diacid monomers in contact with body fluids.
https://rucore.libraries.rutgers.edu/rutgers-lib/24400/PDF/1/play/
Polyanhydride Blends for Drug Delivery, Biofilm Prevention, and Tissue Engineering By MICHELLE LINETTE JOHNSON Dissertation Director: Kathryn E. Uhrich Biodegradable polyanhydrides were fabricated into disks, coatings, microspheres, and tubes for controlled drug delivery as well as enhanced thermal and mechanical properties.
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