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https://www.ncbi.nlm.nih.gov/pubmed/19111339
PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery. Chan JM(1), Zhang L, Yuet KP, Liao G, Rhee JW, Langer R, Farokhzad OC. Author information: (1)Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.Author: Juliana M. Chan, Liangfang Zhang, Kai P. Yuet, Grace Liao, June-Wha Rhee, Robert Langer, Omid C. Far...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954907/
Results. To overcome this challenge, we developed a nano-based approach that uses drug loaded biodegradable nanoparticle (PLGA-PEG PS-341) to provide controlled and sustained drug delivery.The in vitro release kinetics of drug from nanoparticle was quantified by proteasomal activity assay from days 1-7 that showed slow drug release from day 2-7 with maximum inhibition at day 7.Author: Neeraj Vij, Neeraj Vij, Taehong Min, Rhul Marasigan, Christopher N. Belcher, Steven Mazur, Hong Ding...
http://www.julianachan.org/PDF/05-ChanJM.pdf
PLGA–lecithin–PEG core–shell nanoparticles for controlled drug delivery Juliana M. Chana, Liangfang Zhangb, Kai P. Yuetc, Grace Liaoc, June-Wha Rheed, Robert Langerc, Omid C. Farokhzadd,* aDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA b Department of NanoEngineering, University of California-San Diego, La Jolla, CA 92093, USA
https://www.sciencedirect.com/science/article/pii/S037851731500321X
Herceptin conjugated PLGA-PHis-PEG pH sensitive nanoparticles for targeted and controlled drug delivery. ... The effectiveness of drug delivery system can be further enhanced by including targeting ligands to achieve active targeting, which will increase the specificity of a drug delivery system against a cancer of interest. ... Doxorubicin was ...Author: Zilan Zhou, Apurva Badkas, Max Stevenson, Joo-Youp Lee, Yuet-Kin Leung
https://link.springer.com/article/10.1007/s11095-018-2359-8
Feb 09, 2018 · Poly(D,L-lactide-co-glycolide) (PLG) nanoparticles containing doxorubicin and mineralized calcium carbonate were fabricated and their anti-tumor efficacy was tested using a neuroblastoma-bearing mouse model. PLG nanoparticles were prepared by a double emulsion (water-in-oil-in-water; W/O/W) method. Calcium carbonate was mineralized within the PLG nanoparticles during the …Author: Hyeon Jin Jang, Eun Ju Jeong, Kuen Yong Lee
https://phys.org/news/2008-12-gold-nanoparticles-drug-delivery.html
Dec 30, 2008 · Gold nanoparticles for controlled drug delivery The top image shows a mixture of gold nanoparticles. The longer particles are called nanobones, and the smaller are nanocapsules.
http://pubs.acs.org/doi/abs/10.1021/cm3037197
The design of bioresponsive controlled drug delivery systems is a promising approach in cancer therapy, but it still is a major challenge capable of optimum therapeutic efficacy, i.e. no premature drug leakage in blood circulation while having a rapid and complete release in tumor tissues. In this work, a kind of PEGylated core/shell structured composite nanoparticle was developed via ...
https://www.researchgate.net/publication/222526613_PLGA-lecithin-PEG_core-shell_nanoparticles_for_controlled_drug_delivery
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https://www.sciencedirect.com/science/article/pii/S1319016411000302
1. Nanoparticles. Conventional preparations like solution, suspension or emulsion suffer from certain limitations like high dose and low availability, first pass effect, intolerance, instability, and they exhibit fluctuations in plasma drug levels and do not provide sustained effect, therefore there is a need for some novel carriers which could meet ideal requirement of drug delivery system.Author: Sagar R. Mudshinge, Amol B. Deore, Sachin Patil, Chetan M. Bhalgat
https://www.researchgate.net/publication/41850553_Polymeric_Nanoparticles_for_Drug_Delivery
The use of biodegradable polymeric nanoparticles (NPs) for controlled drug delivery has shown significant therapeutic potential. Concurrently, targeted delivery technologies are becoming ...
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