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https://www.ncbi.nlm.nih.gov/pubmed/24568455
Poly (lactic-co-glycolic acid) (PLGA) is one of the most effective biodegradable polymeric nanoparticles (NPs). It has been approved by the US FDA to use in drug delivery systems due to controlled and sustained- release properties, low toxicity, and biocompatibility with tissue and cells.Author: Fatemeh Sadat Tabatabaei Mirakabad, Kazem Nejati-Koshki, Abolfazl Akbarzadeh, Mohammad Rahmati Yamch...
https://www.ncbi.nlm.nih.gov/pubmed/15719481
Nanoparticles represent drug delivery systems suitable for most administration routes. Over the years, a variety of natural and synthetic polymers have been explored for the preparation of nanoparticles, of which Poly(lactic acid) (PLA), Poly(glycolic acid) (PGA), and their copolymers (PLGA) have been extensively investigated because of their biocompatibility and biodegradability.Author: Indu Bala, Sarita Hariharan, Mnv Ravi Kumar
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419218/
Feb 12, 2019 · Poly (lactic-co-glycolic acid) nanoparticles (PLGA NPs) are well recognized as an ideal drug delivery carrier for their biocompatibility and biodegradability. In order to overcome the disadvantage of drug burst release, chitosan (CS) was used to modify the PLGA nanoparticles.Author: Boting Lu, Xikun Lv, Yuan Le
http://journal.waocp.org/article_28622_0df4b374b9a5f9a40363764de4cbbe68.pdf
PLGA-Based Nanoparticles as Cancer Drug Delivery Systems polymer degradation process both in vitro and in vivo is affected by a number of factors, including the method of preparation, the presence of low molecular weight compounds (monomers, oligomers, catalysts), size, shape and morphology, the inherent properties of the polymer
https://www.ncbi.nlm.nih.gov/pubmed/28165858
Drug Deliv. 2017 Nov;24(1):443-451. doi: 10.1080/10717544.2016.1261381. PLGA nanoparticles for the oral delivery of nuciferine: preparation, physicochemical characterization and in vitro/in vivo studies.Author: Ying Liu, Xin Wu, Yushuai Mi, Bimeng Zhang, Shengying Gu, Gaolin Liu, Xiaoyu Li
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827194/
Oct 04, 2019 · Nanoparticles have the ability to dissolve and entrap drugs and have been discovered as desirable drug delivery systems due to their smaller particle size, controlled, and enhanced drug release (1,2). They can be used for various routes of administration including oral, nasal, parenteral, intra-ocular, etc.(3).Author: Parisa Shokoohinia, Marziyeh Hajialyani, Komail Sadrjavadi, Mona Akbari, Masoud Rahimi, Salar Khaled...
https://www.sciencedirect.com/science/article/pii/S1549963409001920
In our current work, we develop and evaluate a new colloidal system, that is, poly(dl-lactide-co-glycolide) (PLGA) nanoparticles for sparfloxacin ophthalmic delivery, to improve precorneal residence time and ocular penetration. Nanoparticles were prepared by nanoprecipitation technique and characterized for various properties such as particle size, zeta potential, in vitro drug release, statistical model fitting, …Author: Himanshu Gupta, Himanshu Gupta, Mohammed Aqil, Roop K. Khar, Asgar Ali, Aseem Bhatnagar, Gaurav Mitt...
http://www.nanovexbiotech.com/858-2/
Poly(lactic-co-glycolic acid) (PLGA) nanoparticles for drug delivery. Poly(lactic-co-glycolic acid) (PLGA) is one of the most commonly used biodegradable synthetic polymer to generate biocompatible nanoparticles since it is a US FDA* and EMA**-approved platform to the delivery of drugs in humans.
https://www.sciencedirect.com/science/article/pii/S0032386115004309
Formulation of functionalized PLGA polymeric nanoparticles for targeted drug delivery 1. Introduction. Since the emergence of nanotechnology, there has been considerable research... 2. Experimental section. N,N′ -Dicyclohexylcarbodiimide (DCC),... 3. Results and discussion. As a starting point for ...Author: Carina I.C. Crucho, Maria Teresa Barros
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Local drug delivery or drug targeting results in increased local drug concentrations and provides strategies for more specific therapy. Nanoparticles have specific particles as tools to enable these strategies. These include benefits such as their small size which allows penetration of cell membranes,...Author: Wim H De Jong, Paul Ja Borm
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