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https://www.sciencedirect.com/science/article/pii/B9780128144275000160
They found that chitosan functionalized CNTs were more effective in the intracellular delivery of peptide compared with chitosan. Chitosan functionalized CNTs significantly increased DNA and peptide delivery to the cells (Zhang et al., 2006). 16.8. Carbon Nanotube–Mediated Gene DeliveryAuthor: Neha Maheshwari, Muktika Tekade, Namrata Soni, Piyush Ghode, Mukesh Chandra Sharma, Pran Kishore Deb...
https://pubs.acs.org/doi/10.1021/mp200523n
The feasibility of cyclo-(d-Trp-Tyr) peptide nanotubes (PNTs) as oral gene delivery carriers was investigated in nude mice with eight 40 μg doses of pCMV-lacZ in 2 days at 3 h intervals. The association between DNA and PNTs, the DNase I stability of PNTs-associated DNA, and in vitro permeability of DNA were estimated. The results showed that the cyclo-(d-Trp-Tyr) PNTs self-associated at ...Author: Wei Hsien Hsieh, Shwu Fen Chang, Hui Min Chen, Jeng Hsien Chen, Jiahorng Liaw
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588189/
In this study, the feasibility of cyclo-(d-Trp-Tyr) peptide nanotubes (PNTs) as carriers of caspase 3 silence shRNA delivery was assessed. A model of epithelial injury by epithelial debridement was applied to investigate the feasibility of PNTs as gene delivery carriers on corneal injury.Author: Yu Hsing Lee, Shwu Fen Chang, Jiahorng Liaw
https://pubs.acs.org/doi/abs/10.1021/mp200523n
The feasibility of cyclo-(d-Trp-Tyr) peptide nanotubes (PNTs) as oral gene delivery carriers was investigated in nude mice with eight 40 μg doses of pCMV-lacZ in 2 days at 3 h intervals. The association between DNA and PNTs, the DNase I stability of PNTs-associated DNA, …Author: Wei Hsien Hsieh, Shwu Fen Chang, Hui Min Chen, Jeng Hsien Chen, Jiahorng Liaw
https://link.springer.com/article/10.1007%2Fs12033-018-0120-5
Sep 10, 2018 · The success of some biological and synthetic nanostructures such as cell-penetrating peptides and carbon nanotubes in transferring macromolecules (proteins and nucleic acids) into mammalian cells provoked us to assess the ability of an engineered chimeric peptide and also arginine functionalized single-walled carbon nanotube in gene delivery to ...Author: Arezoo Golestanipour, Maryam Nikkhah, Ali Aalami, Saman Hosseinkhani
https://en.wikipedia.org/wiki/Self-assembling_peptide
Self-assembling peptide ... this is one example of how peptide nanostructure can in used in gene and drug delivery.It is also envisaged that water-soluble molecules and biological molecules would be ... It has also been found that the catalytic abilities of lipase enzyme is greatly improved when encapsulated in peptide nanotube.
https://www.researchgate.net/publication/223961887_Oral_Gene_Delivery_with_cyclo-D-Trp-Tyr_Peptide_Nanotubes
The feasibility of cyclo-(D-Trp-Tyr) peptide nanotubes (PNTs) as oral gene delivery carriers was investigated in nude mice with eight 40 μg doses of pCMV-lacZ in 2 days at 3 h intervals.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449975/
Apr 28, 2017 · Poly-l-lysine (PLL) is a peptide-based polymer, and was one of the first polymers utilized as a non-viral gene delivery vector. Its peptide structure allows ease of biodegradability and complexes with plasmid DNA to transfect cells. Compared to PEI, however, it has lower transfection efficiency resulting from endosomal capture .Author: Michael K. Riley, Wilfred Vermerris
https://www.sciencedirect.com/topics/chemistry/peptide-nanotube
The peptide nanotube was coated with a metalloporphyrin compound. ... This system will likely have applications for delivery of molecular drugs, including DNA and RNA for gene therapy as well as protein therapy and delivery of other therapeutics. Another system is aiming to produce new biological scaffold material to facilitate biomineralization.
https://www.researchgate.net/publication/281853114_Anti-Apoptotic_Gene_Delivery_with_cyclo-d-Trp-Tyr_Peptide_Nanotube_via_Eye_Drop_Following_Corneal_Epithelial_Debridement
Anti-Apoptotic Gene Delivery with cyclo-(d-Trp-Tyr) Peptide Nanotube via Eye Drop Following Corneal Epithelial Debridement. ... of peptide-based biomaterial is the use of peptide nanotube, ...
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