Peptide Drug Delivery

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Protein and Peptide Drug Delivery: Oral Approaches

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792531/
    Designing and formulating a protein and peptide drug for delivery though GI tract requires a multitude of strategies. The dosage form must initially stabilize the drug making it easy to take orally 4. It must then protect the drug from the extreme acidity and action of pepsin in the stomach.

Oral Peptide Drug Delivery Approach and Methods

    https://zhion.com/pharmaceutics/Oral_Peptide_Delivery.html
    The increases in peptide drug transport are in agreement with a lowering of the transepithelial electrical resistance. No deleterious effect to the cell monolayers could be detected in cell studies. Dosage Forms (Delivery Systems) The primary objective of oral delivery systems for peptides is to protect the protein and peptide drugs from acid and

Protein/Peptide Drug Delivery Systems: Practical ...

    https://www.sciencedirect.com/science/article/pii/B9780128179093000169
    Various protein/peptide drug delivery systems have been extensively investigated to overcome the problems associated with the exogenous administration of protein and peptide therapeutics. In this chapter, different approaches for the delivery of proteins and peptides are discussed including chemical modifications, absorption enhancers, carrier systems, and various other approaches.Author: Pran Kishore Deb, Omar Al-Attraqchi, Balakumar Chandrasekaran, Anant Paradkar, Rakesh K. Tekade

Peptide-based systems for drug delivery - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/B978008100736500017X
    Peptide-based systems are considered one of the tools that may be used in drug and gene delivery. Peptides are small molecules, are easy to obtain, may be chemically modified, are stable in a broad range of biological conditions, are able to cross the plasma membranes of cells and deliver the cargo into the cytosol or the nucleus, and usually do not activate the immune response.Author: Dana M. Copolovici, Andreea I. Lupitu

Peptide Drug Design & Delivery Summit: San Diego, USA ...

    https://finance.yahoo.com/news/peptide-drug-design-delivery-summit-174500297.html
    Mar 03, 2020 · The 2020 Peptide Drug Design & Delivery Summit will bring together key decision-makers and innovators within this rapidly growing field. Hear from over 50 peptide drug commercialization experts on ...

Optimizing the Delivery of Peptide-Based Therapeutics

    https://www.genengnews.com/magazine/297/optimizing-the-delivery-of-peptide-based-therapeutics/
    The Medici Drug Delivery System is a matchstick-sized osmotic minipump that is placed just under the dermal layer of the skin to deliver a continuous and consistent flow of medication. This system, which was developed by Intarcia Therapeutics, allows for proteins, peptides, antibody fragments,...

ORAL PEPTIDE DELIVERY: TECHNOLOGY LANDSCAPE & CURRENT ...

    https://www.ondrugdelivery.com/review-oral-peptide-delivery/
    Injectable sustained-release formulations of peptides demonstrated the power of drug delivery technologies to enhance patient adherence and convenience, and increase safety and efficacy. However, the pain and invasiveness of injections, as well as disposal issues associated with used needles and relatively complicated administration protocols mean that alternative routes of delivery are highly desirable for peptides.

(PDF) PROTEIN AND PEPTIDE DRUG DELIVERY SYSTEM

    https://www.researchgate.net/publication/328265448_PROTEIN_AND_PEPTIDE_DRUG_DELIVERY_SYSTEM
    Protein and Peptide drug delivery system are the Novel drug Delivery System. Proteins and peptides are the most abundant components of biological cells. They exist functioning such as enzymes, hormones, structural element and immunoglobulin. The twenty different naturally occurring amino acids …

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