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https://www.nrcresearchpress.com/doi/10.1139/cjc-2017-0242
Peptide dendrimers comprise interesting classes of dendrimers, and their use has been emphasized as a drug/bioactive compound delivery system, mostly in the antineoplastic area. The bioactive molecules can be covalently linked or entrapped inside the peptide derivative.Author: S.S. Santos, R.V. Gonzaga, J.V. Silva, D.F. Savino, D. Prieto, J.M. Shikay, R.S. Silva, L.H.A. Paulo...
https://www.sciencedirect.com/science/article/pii/B9780128029268000070
Peptide Dendrimers in Transdermal Drug Delivery. Use of peptide dendrimers in transdermal drug delivery was pioneered and widely explored by Mutalik et al. , , , . The first step toward this was the development of a simple, robust, and validated analytical HPLC method for quantifying the dendrimers into and across the skin.Author: Jyothsna Manikkath, Aswathi R. Hegde, Harendra S. Parekh, Srinivas Mutalik
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025585/
Because organs and tumors carry unique marker molecules,27,37 phage display can be used to screen organ- or tumor-specific peptide sequences for targeted drug delivery. The present study used an in vivo phage display method to screen peptides.Author: Jianfeng Liu, Jinjian Liu, Liping Chu, Yanming Wang, Yajun Duan, Lina Feng, Cuihong Yang, Ling Wang,...
https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.201300601
Peptide dendrimers have shown promise as an attractive platform for drug delivery. In this study, mPEGylated peptide dendrimer–doxorubicin (dendrimer–DOX) conjugate‐based nanoparticle is prepared and characterized as an enzyme‐responsive drug delivery vehicle.Author: Chengyuan Zhang, Dayi Pan, Kui Luo, Wenchuan She, Chunhua Guo, Yang Yang, Zhongwei Gu
https://pubs.acs.org/doi/abs/10.1021/ar050203y
The peptide dendrimers were also investigated for drug delivery. Glycopeptide dendrimers conjugated to colchicine selectively inhibited the proliferation of targeted cells, …Author: Tamis Darbre, Jean-Louis Reymond
https://pubs.rsc.org/en/content/articlelanding/2014/py/c4py00601a
In this study, we synthesized and characterized enzyme-responsive mPEGylated peptide dendrimer–GFLG–doxorubicin conjugate (dendrimer–GFLG–DOX) as a chemotherapeutic drug delivery nano-carrier via a two-step highly efficient copper-catalyzed alkyne–azide click cycloaddition (CuAAC) reaction. The tetra-peptide sequence Gly–Phe–Leu–Gly (GFLG) was explored as an enzyme …Author: Chengyuan Zhang, Dayi Pan, Kui Luo, Ning Li, Chunhua Guo, Xiuli Zheng, Zhongwei Gu
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