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https://www.sciencedirect.com/book/9780123849359/peptide-and-protein-delivery
The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics.
https://onlinelibrary.wiley.com/doi/10.1002/anie.201914970
Dec 21, 2019 · A Coordinative Dendrimer Achieves Excellent Efficiency in Cytosolic Protein and Peptide Delivery. Dr. Lanfang Ren. Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241 China. Search for more papers by this author.Author: Lanfang Ren, Jia Lv, Hui Wang, Yiyun Cheng, Yiyun Cheng
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956587/
While peptide delivery by other non-invasive routes (pulmonary, intranasal, buccal, rectal) is being studied, other reviews provide a more complete coverage of these topics. After a peptide therapeutic enters the systemic circulation, it must remain active and reach the correct site/cell type in the body.Author: Benjamin J Bruno, Geoffrey D Miller, Carol S Lim
https://finance.yahoo.com/news/peptide-drug-design-delivery-summit-174500297.html
Mar 03, 2020 · Peptide Drug Design & Delivery Summit: San Diego, USA, August 31st to Sept 2nd, 2020 - Examines Various Peptide Discovery & Synthesis Techniques and …
https://www.sciencedirect.com/science/article/pii/B9780128179093000169
Various protein/peptide drug delivery systems have been extensively investigated to overcome the problems associated with the exogenous administration of protein and peptide therapeutics. In this chapter, different approaches for the delivery of proteins and peptides are discussed including chemical modifications, absorption enhancers, carrier ...Author: Pran Kishore Deb, Omar Al-Attraqchi, Balakumar Chandrasekaran, Anant Paradkar, Rakesh K. Tekade
https://www.ondrugdelivery.com/review-oral-peptide-delivery/
Figure 1: Table summarising selected oral peptide delivery technologies. MERRION’S GIPET ® TECHNOLOGY. Merrion Pharmaceuticals (Dublin, Ireland) is developing the GIPET® technology using an enteric coating (similar to Peptelligence ® and TPE technologies), in order to protect the peptide in the acidic gastric medium and ensure peptide release in the small intestine.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792531/
The main challenge is to improve the oral bioavailability from less than 1% to at least 30-50%. Consequently, efforts have intensified over the past few decades, where every oral dosage form used for the conventional small molecule drugs has been used to explore oral protein and peptide delivery.
http://www.pharmtech.com/considering-protein-and-peptide-delivery
Jan 02, 2019 · “Structural modification with PEGylation, cyclization, chemical conjugation, use of enzyme inhibitors, absorption enhancers, encapsulated carriers, and so on, are all being employed to address the challenges of stability and delivery of protein and peptide therapeutics,” adds Nair.
https://www.nature.com/articles/nchem.2779
May 22, 2017 · Nakase, I. & Futaki, S. Combined treatment with a pH-sensitive fusogenic peptide and cationic lipids achieves enhanced cytosolic delivery of exosomes. Sci. Rep. 5 , 10112 (2015).Author: Misao Akishiba, Toshihide Takeuchi, Yoshimasa Kawaguchi, Kentarou Sakamoto, Hao-Hsin Yu, Ikuhiko Nak...
https://www.optcongress.com/18/Peptide-Discovery/
CHI’s Peptide Discovery and Delivery conference reveals the latest strategies at the forefront of peptide discovery, chemistry and delivery with in-depth sessions on new chemistries, novel delivery mechanisms and the most important preclinical and clinical updates, helping you develop the next-generation of peptides therapeutics, including ...
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