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https://www.researchgate.net/publication/6616613_Pediatric_and_geriatric_drug_delivery
Pediatric and geriatric drug delivery. ... (CBZ) as model drug for pediatric and geriatric compliance. ER-microparticles of carbamazepine, a BCS class 2, and narrow therapeutic index (NTI) drug ...
https://www.ncbi.nlm.nih.gov/pubmed/17184161
Paediatric and geriatric drug delivery. Breitkreutz J(1), Boos J. Author information: (1)Heinrich-Heine-University Düsseldorf, Institute of Pharmaceutics and Biopharmaceutics Universitätsstrasse 1, 40225 Düsseldorf, Germany. [email protected] Age-adapted drug formulations are a challenge in drug development.Author: Jörg Breitkreutz, Joachim Boos
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673516/
Nov 02, 2015 · Introduction: Most conventional drug delivery systems are not acceptable for pediatric patients as they differ in their developmental status and dosing requirements from other subsets of the population. Technology platforms are required to aid the development of age-appropriate medicines to maximize patient acceptability while maintaining safety, efficacy, accessibility and affordability.Author: Felipe L Lopez, Terry B Ernest, Catherine Tuleu, Mine Orlu Gul
https://www.sciencedirect.com/science/article/pii/S0022354917305063
Drug Delivery Innovations to Address Global Health Challenges for Pediatric and Geriatric Populations (Through Improvements in Patient Compliance) Author links ... Liu et al. 7 have suggested the use of fast-melt formulations such as films and wafers for geriatric drug delivery as an alternative to traditional tablets, capsules, and ...Author: Joshua Boateng
https://www.brighttalk.com/webcast/10519/136791/addressing-the-needs-of-a-growing-patient-group-geriatric-oral-drug-delivery
Nov 18, 2015 · Because of worldwide demographic changes a dramatic increase of the geriatric population is expected in the next decades. While pediatric drug delivery principles are becoming integrated into the development of new medicines, drug developers are less prepared to appropriately address the specific needs of this booming patient population.
https://orbisbio.com/age-appropriate-pediatric-and-geriatric-formulation-considerations/
Additionally, many pediatric medications are really scaled-down adult medications. Because of the lack of standardization, these extemporaneous formulations could lead to inaccurate dosing. Drug companies must give special consideration to physiological changes when making formulations for pediatric and geriatric populations.
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