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https://www.ncbi.nlm.nih.gov/pubmed/19126295
CONCLUSIONS: This study suggested that pectin/chitosan microspheres were able to limit the release of vancomycin under acidic conditions and release it under simulated colonic conditions, confirming their potential for a colon-specific drug delivery system.Author: Federica Bigucci, Barbara Luppi, Libera Monaco, Teresa Cerchiara, Vittorio Zecchi
https://onlinelibrary.wiley.com/doi/abs/10.1211/jpp.61.01.0006
Conclusions This study suggested that pectin/chitosan microspheres were able to limit the release of vancomycin under acidic conditions and release it under simulated colonic conditions, confirming their potential for a colon‐specific drug delivery system.Author: Federica Bigucci, Barbara Luppi, Libera Monaco, Teresa Cerchiara, Vittorio Zecchi
https://www.researchgate.net/publication/23761290_Pectin-based_microspheres_for_colon-specific_delivery_of_vancomycin
The aim of this study was to describe a colon-specific delivery system based on pectin hydrogels formed by complexation with chitosan. Hydrogels were prepared at different weight ratios (4:1, 7:1, 10:1; pectin/chitosan), loaded with vancomycin hydrochloride (2:1,...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914573/
It has been reported that colon-specific delivery system of vancomycin HCl based on pectin hydrogels was developed. This study suggested that pectin/chitosan microspheres were able to limit the release of vancomycin under acidic conditions and release it under simulated colonic conditions, confirming their potential for a colon-specific drug delivery system [ 17 ].Author: Kadria A. Elkhodairy, Kadria A. Elkhodairy, Samar A. Afifi, Azza S. Zakaria, Azza S. Zakaria
https://www.researchgate.net/publication/276022774_Pectin-based_colon-specific_drug_delivery
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https://link.springer.com/article/10.1007/s12272-012-1109-4
Dec 04, 2012 · The purpose of this study was to develop and evaluate a colon-specific, pulsatile drug delivery system, which consists of an impermeable capsule body filled with a 5-aminosalicylic acid rapid-disintegrating tablet and a pectin-based erodible plug placed in the opening of the capsule body.Author: Jing Liu, Liangke Zhang, Yuntao Jia, Wenjing Hu, Jingqing Zhang, Huiming Jiang
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