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https://www.researchgate.net/publication/226169622_PAMAM_Dendrimers_as_Nanoscale_Oral_Drug_Delivery_Systems
Dendrimers are highly branched macromolecules of low polydispersity that provide many exciting opportunities for design of novel drug-carriers, gene delivery systems and imaging agents.
https://link.springer.com/chapter/10.1007/978-0-387-77668-2_14
Nanomaterials used as drug delivery systems, also termed nanocarriers, should be freely permeable to tumor vasculature since the endothelial pores range from 100 to 1000 nm (Hobbs et al., 1998). On the other hand, several moieties can be incorporated in these nanocarriers to enhance the delivery of bioactive and diagnostic agents.Author: Kelly M. Kitchens, Hamidreza Ghandehari
https://www.sciencedirect.com/science/article/pii/S2352940718301641
The current paper has provided an overview of PAMAM-based drug and gene delivery or co-delivery systems using active targeting in both in vitro and in vivo conditions, and it can be concluded that this class of nanocarrier exhibits high potential for targeted cancer therapy.Author: Fereydoon Abedi-Gaballu, Fereydoon Abedi-Gaballu, Gholamreza Dehghan, Maryam Ghaffari, Maryam Ghaffa...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/oral-drug-delivery
Umesh Gupta, Omathanu Perumal, in Natural and Synthetic Biomedical Polymers, 2014. 15.5.1.2 Oral Drug Delivery. Oral drug delivery is the most preferred drug administration route due to convenience, cost-effectiveness, and high patient compliance. The challenges in oral drug delivery include aqueous solubility, membrane permeability, and chemical and enzymatic stability of drugs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694674/
Dendrimers as tunable vectors of drug delivery systems and biomedical and ocular applications. ... Their body excretion mode is a function of their nanoscale diameter, and can be well controlled and monitored. ... Oral drug delivery. PAMAM-based dendrimers with or without surface modifications were studied for oral drug delivery.Author: Marina Kalomiraki, Kyriaki Thermos, Nikos A Chaniotakis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097927/
Dendrimers for Drug Delivery and Targeting. The precise control over the distribution of drugs is highly valuable to abolish the typical drawbacks of traditional medicine. Thus, a drug delivery system should be designed to attain the site-specific delivery preferentially.
https://www.researchgate.net/publication/324596447_Dendrimers_for_Drug_Delivery
The aim of this investigation was to evaluate the in vivo potential of poly (amido) amine dendrimers (PAMAM) based simvastatin (SMV) formulations as nanoscale drug delivery units for controlled ...Author: Abhay Singh Chauhan
http://ijpsr.com/bft-article/nano-drug-delivery-systems-a-review/?view=fulltext
At present, one of the most attractive areas of research in drug delivery is the design of ‘Nano drug delivery systems’ that are able to deliver drugs to the right place, at appropriate time. In the present review article different nano carriers are explained (Nanoparticles, nanocapsules, nanocrystals, nanoemulsion, dendrimers, polymeric ...
https://chemistry.illinois.edu/system/files/inline-files/Brummond.pdf
APPLICATIONS OF DENDRIMERS TO DRUG DELIVERY Reported by: Catherine A. Brummond March 4, 2004 INTRODUCTION The discovery and creation of new drugs is timely and costly process. It is estimated that every new drug takes 12 to 15 years to develop, at a cost of over $800 million.1,2 A more efficient approach
https://drum.lib.umd.edu/bitstream/handle/1903/11163/Goldberg_umd_0117E_11719.pdf;sequence=1
POLY (AMIDO AMINE) DENDRIMERS: TRANSEPITHELIAL TRANSPORT MECHANISMS AND APPLICATIONS IN ORAL DRUG DELIVERY By Deborah Sweet Goldberg Dissertation submitted to the Faculty of the Graduate School of the University of Maryland, College Park, in partial fulfillment of the requirements for the degree of Doctor of Philosophy 2010 Advisory Committee:
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