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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171204/
Oral delivery technologies have the potential to have a significant impact on the treatment of many diseases by enabling therapeutics currently limited to parenteral administration to be administered through the oral route. There are currently several different polymeric NP approaches being studied to overcome the barriers of the intestine.Author: Eric M. Pridgen, Frank Alexis, Omid C. Farokhzad, Omid C. Farokhzad
http://jpet.aspetjournals.org/content/early/2019/04/22/jpet.118.255828
Jan 01, 2019 · Advanced drug delivery technologies in general can enable drug reformulation and administration routes, together contributing to life-cycle management allowing the innovator to maintain the product monopoly. Over the years there has been a steady shift from mere life-cycle management to drug re-purposing, or applying delivery technologies to tackle solubility and permeability issues in …Author: G. Kaur, M. Arora, M.N.V. Ravi Kumar
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835173/
Oral delivery technologies can be used to treat diseases of the gastrointestinal (GI) tract locally or to enable therapeutics to reach systemic circulation. For therapeutics to reach the bloodstream after oral administration, they must pass through the gastrointestinal (GI) tract and be absorbed.Author: Eric M Pridgen, Frank Alexis, Omid Cameron Farokhzad
https://www.ondrugdelivery.com/review-oral-peptide-delivery/
PROTEIN ORAL DELIVERY TECHNOLOGY POD ™ POD technology developed by Oramed (Jerusalem, Israel), consists of enteric-coated capsules containing an oily suspension of the peptide drug, an enzyme inhibitor, such as soy bean trypsin inhibitor, aprotinin and an absorption enhancer such as EDTA or bile salt, in omega-3 fatty acids.
https://otd.harvard.edu/explore-innovation/technologies/oral-delivery-of-biologics
As oral delivery is associated with high compliance and low cost, one potential solution would be to deliver biologics orally (while simultaneously preserving their systemic effects). The Mitragotri laboratory at Harvard has developed a novel platform technology to systemically deliver biologics after oral …
https://emisphere.com/improved-oral-delivery-eligen/
Eligen Technology has demonstrated therapeutic levels of heparin can be reached has shown comparable efficacy to injected Lovenox. Oral Human Growth Hormone Human Growth Hormone (hGH) is a protein hormone that stimulates tissue growth and …
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