We have collected information about Ocular Route For Insulin Delivery for you. Follow the links to find out details on Ocular Route For Insulin Delivery.
http://jpet.aspetjournals.org/content/249/1/249
Apr 01, 1989 · The ocular route for systemic insulin delivery in the albino rabbit. A Yamamoto , A M Luo , S Dodda-Kashi and V H Lee Journal of Pharmacology …Author: A. Yamamoto, A. M. Luo, Satish Dodda-Kashi, V. H. L. Lee
https://www.sciencedirect.com/science/article/pii/S0378517301009206
A wide variety of absorption enhancers have been evaluated in the delivery of insulin via the ocular route. Some of these are listed in Table 3. As seen in the table, saponin and its derivatives are commonly used as absorption enhancers in the ocular delivery of insulin. The in vivo data indicate that saponin is a strong absorption enhancer.Author: Yung Chi Lee, Pahala Simamora, Sirirat Pinsuwan, Samuel H Yalkowsky
https://www.liebertpub.com/doi/abs/10.1089/jop.1995.11.565
Insulin delivered alone and in the presence of Brij-99 did not significantly alter glucose and insulin concentrations. While effective as an absorption enhancer, 0.5% saponin caused transient ocular irritation in all the test subjects. Brij-99 was also irritating to some of the cats.Author: Rhea V. Morgan, Marcy A. Huntzicker
https://www.liebertpub.com/doi/abs/10.1089/jop.1996.12.515
Insulin delivered alone and in the presence of 0.5% Brij-78 and 0.5% fusidic acid did not significantly alter glucose and/or insulin concentrations. Solutions containing 0.5% saponin induced signs of ocular irritation for approximately 5 minutes.Author: Rhea V. Morgan, Marcy A. Huntzicker
https://arizona.pure.elsevier.com/en/publications/review-on-the-systemic-delivery-of-insulin-via-the-ocular-route
Systemic drug absorption from the ocular route is well known. Although there is some absorption from the conjunctival sac, the nasal meatus is the site where the majority of systemic absorption of instilled drug takes place. This article reviews the principles of systemic absorption of insulin applied topically to …Author: Yung Chi Lee, Pahala Simamora, Sirirat Pinsuwan, Samuel H Yalkowsky
https://www.researchgate.net/publication/11467139_Review_on_the_systemic_delivery_of_insulin_via_the_ocular_route
Systemic drug absorption from the ocular route is well known. Although there is some absorption from the conjunctival sac, the nasal meatus is the site where the majority of systemic absorption of instilled drug takes place. This article reviews the principles of systemic absorption of insulin applied topically to …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374550/
The ocular route may also be used for the systemic delivery of peptides and protein based pharmaceutical drugs. The ocular route is the choice for the localized delivery of ophthalmologically active peptide and protein for the treatment of ocular disease in the pharmaceutical dosage form of solutions, suspensions and ointment.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787057/
Trans-dermal insulin delivery eliminates the problems associated with needles and injections and large surface area of the skin makes it a convenient route for insulin delivery. However, the penetration of insulin is halted by the stratum corneum, the outer most layer of the skin.
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/nanoparticle-insulin-drug-delivery-applications-and-new-aspects
Delivery route of insulin 2.1. Oral delivery. 2.2. Nasal delivery. 2.3. Pulmonary delivery. 2.4. Buccal delivery. 2.5. Transdermal delivery. 2.6. Ocular delivery. 2.7. Vaginal delivery. 2.8. Rectal delivery.Author: Hatice Kübra Elçioğlu, Ali Demir Sezer
https://www.sciencedirect.com/science/article/pii/S0168365997000746
1. Introduction. Peptide and drug delivery through the ocular 1, 2and nasal 3, 4routes of administration has increased in recent years. Of particular interest is the delivery of peptides and proteins through these routes, as it is known that peptidase activity is reduced or minimized in the nasal cavity or the eyes , thus allowing a significant absorption of the bioactive agent.Author: Yoshie Maitani, Tsuneji Nagai, Kyle Kollias, Nikolaos A Peppas
Searching for Ocular Route For Insulin Delivery?
You can just click the links above. The data is collected for you.
