Ocular Delivery Using Prodrugs

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Prodrug Strategies in Ocular Drug Delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407659/
    So far folate receptor has been utilized as an ideal candidate for tumor targeted drug delivery but less attention has been given to receptor theory for ocular drug delivery . Recently our laboratory has started working on the extension of targeted prodrug approach by synthesizing receptor targeted prodrugs for ocular drug delivery.Author: Megha Barot, Mahuya Bagui, Mitan R. Gokulgandhi, Ashim K. Mitra

Prodrugs for improved ocular drug delivery - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/0169409X9500107I
    advanced drug delivery reviews ELSEVIER Advanced Drug Delivery Reviews. 19 (1996) 203-224 Review Prodrugs for improved ocular drug delivery Tomi Jarvinen'1'*, Kristiina Jarvinen1' "Department of Pharmaceutical Chemistry. University of Kuopio, P.O. Box 1627, 70211, Kuopio, Finland ''Department of Pharmaceutics, University of Kuopio, Kuopio.Author: Tomi Järvinen, Kristiina Järvinen

Prodrugs and Targeted Delivery: Towards Better ADME ...

    https://www.wiley.com/en-us/Prodrugs+and+Targeted+Delivery%3A+Towards+Better+ADME+Properties-p-9783527326037
    OCULAR DELIVERY USING PRODRUGS Introduction Criteria for an Ideal Ophthalmic Prodrug Anatomy and Physiology of the Eye Barriers to Ocular Drug Delivery Influx and Efflux Transporters on the Eye Transporter-Targeted Prodrug Approach Drug Disposition in Ocular Delivery Effect of Physiochemical Factors on Drug Disposition in Eye

Ocular Drug Delivery - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
    May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra

Advances in the use of prodrugs for drug delivery to the ...

    https://www.researchgate.net/publication/305497841_Advances_in_the_use_of_prodrugs_for_drug_delivery_to_the_eye
    Advances in the use of prodrugs for drug delivery to the eye. ... These results suggest that novel long chain lipid GCV prodrugs may be further evaluated for ocular delivery and treatment of HCMV ...

Prodrug Strategies in Ocular Drug Delivery Request PDF

    https://www.researchgate.net/publication/224834657_Prodrug_Strategies_in_Ocular_Drug_Delivery
    Prodrug Strategies in Ocular Drug Delivery. Article · Literature Review ... There is also brief account of other types of prodrugs used for improving ocular bioavailability. View.

USING PHYSICAL FORCES TO ENHANCE OCULAR DRUG DELIVERY ...

    https://www.ondrugdelivery.com/7049-2/
    Citation: Huang D, Chen E, Rupenthal ID, “Using Physical Forces to Enhance Ocular Drug Delivery”. ONdrugDelivery Magazine, Issue 82 (Jan 2018), pp 6-9. ... Formulation-based approaches include chemical penetration enhancers, prodrugs and drug delivery carriers such as liposomes and nano- or microparticles able to penetrate the ocular ...

Prodrugs And Targeted Delivery Pdf - Acquire

    http://diecarcentnagol.weebly.com/blog/prodrugs-and-targeted-delivery-pdf
    Ocular Delivery Using Prodrugs - Prodrugs and Targeted Delivery: Towards Better ADME Properties - Kwatra. Introduction. Criteria for an Ideal Ophthalmic Prodrug. Anatomy and Physiology of the Eye. Barriers to Ocular Drug Delivery. Influx and Efflux Transporters on the Eye. Transporter- Targeted Prodrug Approach. Drug Disposition in Ocular Delivery.

Drug Delivery System - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
    Colonic-targeted drug delivery is useful for the treatment of inflammatory bowel diseases. In this case, the systems have been developed using pH-dependent delivery, enzyme-dependent delivery (for prodrugs, matrices, and coatings), pulsatile time-dependent delivery, and pressure-dependent delivery approaches (Bansal et al., 2014).

Pilocarpic acid esters as novel sequentially labile ...

    https://pubs.acs.org/doi/abs/10.1021/jm00146a001
    Prodrugs for improved ocular drug delivery. Advanced Drug Delivery Reviews 1996, 19 (2) , 203-224. DOI: 10.1016/0169-409X(95)00107-I. Hitoshi Sasaki, Kenzo Yamamura, Koyo Nishida, Junzo Nakamura, Masataka Ichikawa. Delivery of drugs to the eye by topical application.Author: Hans Bundgaard, Erik Falch, Claus Larsen, Gerold L. Mosher, Thomas J. Mikkelson

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