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https://www.sciencedirect.com/science/article/pii/S0169409X04002686
Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer. Author links open overlay panel ... appears to circumvent many problems associated with DNA and drug based methods. ... L. Wylie, P.A. WenderArginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular ...Author: Jehangir S. Wadia, Steven F. Dowdy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
https://www.sciencedirect.com/science/article/pii/S0168365916301523
CPPs can also be used in combination with other drug vectors, fused with their preponderances to create novel multifunctional drug-delivery systems that increase the stability during blood circulation, and also develop novel preparations capable of targeted delivery, along with sustainable and controllable release.Author: Dongdong Zhang, Jiaxi Wang, Donggang Xu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990626/
Jan 28, 2020 · Transmembrane TNFα, a crucial signaling cytokine, holds anticell proliferative potential. Successful delivery of this intact transmembrane protein to the target site is quite intriguing. Amidst numerous nanocarriers, a novel class of new generation ...
https://www.nature.com/articles/s41589-020-0483-3
A set of CRISPR–Cas9-based genetic screens in a haploid human cell line identifies more than 200 gene–drug associations involving solute carriers (SLCs), transporters important for the uptake ...Author: Enrico Girardi, Adrián César-Razquin, Sabrina Lindinger, Konstantinos Papakostas, Justyna Konecka, J...
https://quizlet.com/147812928/drug-delivery-exam-1-flash-cards/
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https://techtransfer.cancer.gov/availabletechnologies/e-256-2006
They inhibit metastasis, reduce inflammation or reverse drug resistance thus sensitizing tumors to therapy. Particles allow for easy attachments of tumor-selective ligands, therapeutic agents and can encapsulate hydrophobic drugs – thus addressing the problem of selective tumor delivery.
https://www.nature.com/articles/nrd.2015.21
Jan 22, 2016 · Research in the past few decades has revealed that the BBB is not only a substantial barrier for drug delivery to the CNS but also a complex, dynamic interface that …Author: William A. Banks
https://www.jgtps.com/admin/uploads/YqxI0h.pdf
drugs. The development of new delivery systems for the controlled release of drugs is one of the most interesting fields of research in pharmaceutical sciences. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a …File Size: 1MB
https://academic.oup.com/neuro-oncology/article/18/1/27/2509241
Sep 10, 2015 · Treatment of GBM is a formidable challenge. The intense investigation of numerous strategies to improve drug delivery in the context of GBM reflects the difficulty posed by the BBB, which provides both physical and biochemical barriers that limit …Author: Rajneet K. Oberoi, Karen E. Parrish, Terence T. Sio, Rajendar K. Mittapalli, William F. Elmquist, Ja...
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