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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
To overcome the ocular drug delivery barriers and improve ocular bioavailability, various conventional and novel drug delivery systems have been developed such as emulsion, ointments, suspensions, aqueous gels, nanomicelles, nanoparticles, liposomes, dendrimers, implants, contact lenses, nanosuspensions, microneedles, and in situ ...Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306122/
Dec 26, 2010 · To overcome the above-mentioned limitations, an increasing number of sustained-release drug delivery devices using different mechanisms and containing a variety of agents have been developed to treat uveitis. This review discusses various current and future sustained-release ophthalmic drug delivery systems for treatment of uveitis.Author: Nahid Haghjou, Masoud Soheilian, Mohammad Jafar Abdekhodaie
https://eye.hms.harvard.edu/topic/drug-delivery-medical-devices
Drug Delivery and Medical Devices Publications. Jumelle C, Gholizadeh S, Annabi N, Dana R. ... Contact lens drug delivery may become an option for the treatment of glaucoma and a platform for ocular drug delivery. Modjtahedi BS, van Zyl T, Pandya HK, Leonard RE, Eliott D.
Use of corticosteroids including OZURDEX ® may produce posterior subcapsular cataracts, increased eye pressure, glaucoma, and may increase the establishment of secondary eye infections due to bacteria, fungi, or viruses. Let your doctor know if you have a history of ocular herpes simplex as corticosteroids are not recommended in these patients.
https://www.arvo.org/globalassets/annual-meeting/program/education-courses/2020-agenda---ocular-drug-delivery.pdf
Ocular drug delivery: Fundamentals, challenges, and technologies Organizers Ash Jayagopal, PhD, Kodiak Sciences Inc. and Uday Kompella, PhD, University of Colorado, Anschutz Medical Campus Description Ocular drug delivery is an evolving field featuring cutting-edge advances in devices, formulations, and paradigms for design and characterization.
https://pharm.ucsf.edu/desai/research/ocular-drug-delivery
One attractive platform for continuous delivery of antibody-based therapeutics is the use of nanoporous materials. We are developing injectable nanoporous devices for long-term drug delivery to the eye. Current efforts are directed toward tuning our devices for constant drug release and timely degradation.
https://www.sciencedirect.com/science/article/pii/S0169409X17300996
Mar 15, 2018 · Drug delivery devices for retinal diseases ... The refillable property of implant devices is an important direction of ocular drug delivery studies and will be further discussed later in Section 4.1. While the biodegradable and non-biodegradable devices described above …Author: Hirokazu Kaji, Nobuhiro Nagai, Matsuhiko Nishizawa, Toshiaki Abe
http://biomems.usc.edu/publications/2009/2009_BioMicroDev_ocular_drug_delivery.pdf
1.2 Conventional ocular drug delivery devices Existing ocular drug delivery devices can be categorized as (1) biodegradable or non-biodegradable, (2) atypical im-plantable systems, and (3) implantable pump systems. Biodegradable and non-biodegradable systems typically consist of a polymer matrix infused with drug or a reservoir
https://www.researchgate.net/publication/230736011_Design_of_an_Implantable_Device_for_Ocular_Drug_Delivery
There is an increasing need to develop implantable drug delivery devices for effective therapeutic management of chronic ocular diseases such as age-related macular degeneration (AMD).
https://www.liebertpub.com/doi/full/10.1089/jop.2012.0212
In the ocular pharmacology market, there is a noteworthy unmet demand for more efficacious delivery of ocular therapeutics. Contact lenses are emerging as an alternative ophthalmic drug delivery system to resolve the drawbacks of the conventional topical application methods.Author: Ana Guzman-Aranguez, Basilio Colligris, Jesús Pintor
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