We have collected information about Nonviral Vectors For Gene Delivery for you. Follow the links to find out details on Nonviral Vectors For Gene Delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · There are different viral and nonviral vectors for gene delivery, but all gene therapy applications depend on the fact that the genetic material needs to be delivered across the cell membrane and ultimately to the cell nucleus.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782077/
Oct 16, 2009 · Gene therapy is becoming a promising therapeutic modality for the treatment of genetic and acquired disorders. Nonviral approaches as alternative gene transfer vehicles to the popular viral vectors have received significant attention because of their favorable properties, including lack of immunogenicity, low toxicity, and potential for tissue specificity.Author: Mohammed S. Al-Dosari, Xiang Gao
https://pubs.acs.org/doi/10.1021/cr800409e
Dec 03, 2008 · Cationic Amino Acid Based Lipids as Effective Nonviral Gene Delivery Vectors for Primary Cultured Neurons. ACS Chemical Neuroscience 2013, 4 (12) , 1514-1519. DOI: 10.1021/cn400036j. Yang Yang, Ying-Ming Zhang, Yong Chen, Jia-Tong Chen, and Yu Liu .Author: Meredith A. Mintzer, Eric E. Simanek
http://www.genetherapynet.com/non-viral-vectors.html
To improve the delivery of the new DNA into the cell, the DNA must be protected from damage and its entry into the cell must be facilitated.To this end new molecules, lipoplexes and polyplexes, have been created that have the ability to protect the DNA from undesirable degradation during the transfection process.. Plasmid DNA can be covered with lipids in an organized structure like a micelle ...
https://www.nature.com/articles/nrg3763
Jul 15, 2014 · A direct comparison of two nonviral gene therapy vectors for somatic integration: in vivo evaluation of the bacteriophage integrase phiC31 and the Sleeping Beauty transposase. Mol. Ther. 11 , …Author: Hao Yin, Rosemary L. Kanasty, Ahmed A. Eltoukhy, Arturo J. Vegas, Arturo J. Vegas, J. Robert Dorkin,...
https://www.nature.com/articles/3301923
Nov 29, 2002 · The development of gene carriers for effectively delivering genes into cells has attracted a great deal of attention in recent years. Nonviral vectors should circumvent some of the problems ...Author: T Niidome, L Huang
https://pubs.acs.org/doi/10.1021/ar200151m
Successful gene therapy is thus dependent on the development of an efficient delivery vector.Researchers have pursued two major vehicles for gene delivery: viral and nonviral (synthetic) vectors. Although viral vectors currently offer greater efficiency, nonviral vectors, which are typically based on cationic lipids or polymers, are preferred ...Author: Xia Guo, Leaf Huang
https://www.intechopen.com/books/gene-therapy-tools-and-potential-applications/non-viral-delivery-systems-in-gene-therapy
Gene delivery systems include viral vectors and non-viral vectors. Viral vectors are the most effective, but their application is limited by their immunogenicity, oncogenicity and the small size of the DNA they can transport. ... (February 27th 2013). Non-Viral Delivery Systems in Gene Therapy, Gene Therapy - Tools and Potential Applications ...Author: Alicia Rodríguez Gascón, Ana del Pozo-Rodríguez, María Ángeles Solinís
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