Nonviral Gene Therapy Polycation-Mediated Dna Delivery

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Non-viral gene therapy: polycation-mediated DNA delivery ...

    https://link.springer.com/article/10.1007%2Fs00253-003-1321-8
    Apr 29, 2003 · Gene therapy, i.e., the expression in cells of genetic material with therapeutic activity, holds great promise for the treatment of human diseases. A delivery vehicle (vector), of either viral or non-viral origin, must be used to carry the foreign gene into a cell. Viral vectors take advantage of the facile integration of the gene of interest into the host and high probability of its long-term ...Author: M. Thomas, A. M. Klibanov

Non-viral gene therapy: Polycation-mediated DNA delivery

    https://www.researchgate.net/publication/7388176_Non-viral_gene_therapy_Polycation-mediated_DNA_delivery
    Download Citation Non-viral gene therapy: Polycation-mediated DNA delivery Gene therapy, i.e., the expression in cells of genetic material with therapeutic activity, holds great promise for ...

Non-viral vectors for gene-based therapy Nature Reviews ...

    https://www.nature.com/articles/nrg3763
    Jul 15, 2014 · Thomas, M. & Klibanov, A. M. Non-viral gene therapy: polycation-mediated DNA delivery. Appl. ... A. Breaking up the correlation between efficacy and toxicity for nonviral gene delivery.Author: Hao Yin, Rosemary L. Kanasty, Ahmed A. Eltoukhy, Arturo J. Vegas, Arturo J. Vegas, J. Robert Dorkin,...

Non-Viral Gene Therapy IntechOpen

    https://www.intechopen.com/books/non-viral-gene-therapy
    This book focuses on recent advancement of gene delivery systems research. With the multidisciplinary contribution in gene delivery, the book covers several aspects in the gene therapy development: various gene delivery systems, methods to enhance delivery, materials with modification and multifunction for the tumor or tissue targeting. This book will help molecular biologists gain a basic ...Author: Xu-bo Yuan

Nonviral Gene Therapy: The Promise of Genes as ...

    https://www.liebertpub.com/doi/10.1089/hum.1995.6.9-1129
    Various methods for nonviral gene therapy have been proposed. Some approaches are aimed at developing “artificial viruses” that attempt to mimic the process of viral infection using synthetic materials. Others apply the theory and methods of advanced, particulate …Author: Fred D. Ledley

(PDF) Non-viral vectors for gene-based therapy

    https://www.researchgate.net/publication/263935637_Non-viral_vectors_for_gene-based_therapy
    Non-viral vectors for gene-based therapy. ... However, DNA delivery must also provide transport . into the nucleus to allow access to the transcriptional . machinery (FIG. 1). It was reported ...

Nonviral Vectors for Gene Therapy, Volume 88 - 1st Edition

    https://www.elsevier.com/books/nonviral-vectors-for-gene-therapy/huang/978-0-12-800148-6
    Purchase Nonviral Vectors for Gene Therapy, Volume 88 - 1st Edition. Print Book & E-Book. ISBN 9780128001486, 9780128003671

Non-viral gene therapy: polycation-mediated DNA delivery ...

    https://www.deepdyve.com/lp/springer-journals/non-viral-gene-therapy-polycation-mediated-dna-delivery-ee6CGU4gEd
    Apr 29, 2003 · Read "Non-viral gene therapy: polycation-mediated DNA delivery, Applied Microbiology and Biotechnology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

Polycation‐mediated gene delivery: Challenges and ...

    https://www.onlinelibrary.wiley.com/doi/pdf/10.1002/elsc.201400043
    Polycation-mediated gene delivery: Challenges and considerations for the process of plasmid ... over 1900 approved gene therapy clini-cal trials have been conducted worldwide since the first trial back in 1989; however, only two of these trials (0.1%) have ... be …Author: Karl Modra, Sheng Dai, Hu Zhang, Bingyang Shi, Jingxiu Bi

Effective PEI-mediated delivery of CRISPR-Cas9 complex for ...

    https://www.sciencedirect.com/science/article/pii/S1549963418304830
    Based on research into PEI isoform-mediated gene therapy in the cochlea and PEI based delivery of plasmid DNA in vivo,33, 34, 35 it may be possible to deliver Cas9 directly to the inner ear of diseased animal models using this material to rescue genetic disorders. However, in many applications, delivery of a large amount of plasmid vector would ...Author: Nari Ryu, Nari Ryu, Min-A Kim, Min-A Kim, Dongsik Park, Byeonghyeon Lee, Byeonghyeon Lee, Ye-Ri Kim,...

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