Nasal Delivery Of Progesterone

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Carbopol-Based Gels for Nasal Delivery of Progesterone

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628265/
    CD complex promotes the nasal absorption of progesterone from carbopol gels as compared with gels where the CD is added by simple addition and gels which do not contain CD. This method of addition of CD as an inclusion complex in the gels could be considered as a preferred platform in nasal drug …Author: Grace Rathnam, N. Narayanan, R. Ilavarasan

Nasal delivery of progestational steroids in ...

    https://www.sciencedirect.com/science/article/pii/037851738890018X
    Transnasal delivery of progesterone was studied in rabbits employing a nasal spray and a specially designed controlled delivery nasal device. The device is cylindrically shaped for better insertion into the nasal cavity, and is walled with a microporous membrane to permit controlled delivery of progesterone from a suspension formulation to the nasal mucosa.Author: Diane C. Corbo, Yih C. Huang, Yie W. Chien

Intranasal delivery of progesterone after transient ...

    https://www.sciencedirect.com/science/article/pii/S0028390815002580
    Progesterone was administered intranasally or intraperitoneally at the dose of 8 mg/kg. Nasal delivery was performed without anesthesia by direct application of progesterone oleogel into each nostril (1 μl/nostril/10 g of body weight) using a pipette. Mice were randomly assigned to …Author: Magalie Fréchou, Shaodong Zhang, Philippe Liere, Brigitte Delespierre, Nouha Soyed, Antoine Pianos, ...

Progesterone administration by nasal spray

    https://www.fertstert.org/article/S0015-0282(16)54433-1/pdf
    and nasal mucosa metabolism. Currently, the overall effect of the estrogens in­ fluence on the nasal absorption of sex steroid hor­ mones is still unknown. The estrogens increase the nasal vascularization favoring the drug absorption but also the mucosal interstitial hydration and the mucous blanket production,6 probably interfering

(PDF) Carbopol-Based Gels for Nasal Delivery of Progesterone

    https://www.researchgate.net/publication/23315156_Carbopol-Based_Gels_for_Nasal_Delivery_of_Progesterone
    Nasal delivery is needle-free, non-invasive, and painless; it does not require sterile preparation, can be self-administered, and facilitates the rapid onset of both local and systemic drug action.

Carbopol-Based Gels for Nasal Delivery of Progesterone ...

    https://link.springer.com/article/10.1208%2Fs12249-008-9144-7
    Oct 11, 2008 · The purpose of this study was to investigate the nasal absorption of progesterone from carbopol-based nasal gels in rabbits. Progesterone nasal gels were p The potential use of β cyclodextrin (CD) as nasal absorption enhancer by simple addition, as a physical mixture and as a complex with progesterone was investigated.Author: Grace Rathnam, N. Narayanan, R. Ilavarasan

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