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https://www.ncbi.nlm.nih.gov/pubmed/19488722
Nanoparticle-mediated gene delivery. Jin S(1), Leach JC, Ye K. Author information: (1)College of Engineering, University of Arkansas, Fayetteville, AR, USA. Nonviral gene delivery has been gaining considerable attention recently. Although the efficacy of DNA transfection, which is a major concern, is low in nonviral vector-mediated gene ...Author: Sha Jin, John C. Leach, Kaiming Ye
https://www.intechopen.com/books/advanced-technology-for-delivering-therapeutics/medicated-nanoparticle-for-gene-delivery
Medicated Nanoparticle for Gene Delivery, Advanced Technology for Delivering Therapeutics, Sabyasachi Maiti and Kalyan Kumar Sen, IntechOpen, DOI: 10.5772/65709. Available from: Over 21,000 IntechOpen readers like this topic. Help us write another book …Author: Sakthivel Lakshmana Prabu, Timmadonu Narasimman KuppusamiSuriyaprakash, Rathinasabapathy Thirumuruga...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046008/
May 21, 2014 · Nanoparticles in gene delivery. In the field of nanomedicine, nanotechnology methods focus on formulating therapeutic biocompatible agents such as nanoparticles, nanocapsules, micellar systems, and conjugates [22,23].Nanoparticles are solid and spherical structures ranging to around 100 nm in size and prepared from natural or synthetic polymers [].Author: Solmaz Maleki Dizaj, Samira Jafari, Ahmad Yari Khosroushahi
https://engineering.jhu.edu/materials/research-projects/polymeric-nanoparticles-for-gene-delivery/
Polymeric Nanoparticles for Gene Delivery. ... An ability to control nanoparticle stability, DNA or RNA release, cell binding, and intracellular trafficking will be the key to understanding the rate-limiting steps for gene delivery and to optimizing transgene expression efficiency in vivo. ... Department of Materials Science and Engineering ...
https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(16)30165-6
Jan 01, 2016 · Gene therapy is a promising strategy for specific treatment of numerous gene-associated human diseases by intentionally altering the gene expression in pathological cells. A successful clinical application of gene-based therapy depends on an efficient gene delivery system. Many efforts have been attempted to improve the safety and efficiency of gene-based therapies. Nanoparticles have been ...Author: Jie Chen, Zhaopei Guo, Huayu Tian, Xuesi Chen
https://pubs.acs.org/doi/10.1021/acsnano.8b08177
Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. Gulsah Erel-Akbaba. Gulsah Erel-Akbaba. Experimental Therapeutics and Molecular Imaging Lab, Department of Neurology, Neuro-Oncology Division, Massachusetts General Hospital, Charlestown, Massachusetts 02129, United States ...Author: Gulsah Erel-Akbaba, Litia A. Carvalho, Tian Tian, Tian Tian, Max Zinter, Hasan Akbaba, Hasan Akbaba,...
https://www.youtube.com/watch?v=SZIBFWmQqBc
Sep 13, 2017 · Delivering DNA into a cell isn't easy. To overcome this challenge the laboratory of Dr. Jordan Green at Johns Hopkins University has come up with a solution; pack the genetic material into a ...Author: INBT Johns Hopkins
https://www.researchgate.net/publication/26259469_Nanoparticle-Mediated_Gene_Delivery
Nonviral gene delivery has been gaining considerable attention recently. Although the efficacy of DNA transfection, which is a major concern, is low in nonviral vector-mediated gene transfer ...
https://www.sciencedirect.com/science/article/abs/pii/S0168365915301772
Nonviral gene delivery to the liver has been under evolution for nearly 30 years. Early demonstrations established relatively simple nonviral vectors could mediate gene expression in HepG2 cells which understandably led to speculation that these same vectors would be immediately successful at transfecting primary hepatocytes in vivo.
https://www.sciencedirect.com/science/article/pii/S1773224717300564
The last years have witnessed an impressive development of material sciences following the burst of nanotechnology, which has greatly contributed to the development of nonviral gene delivery systems with improved properties for the efficient transport of nucleic acid payloads for gene therapy purposes.Author: José L. Jiménez Blanco, Juan M. Benito, Carmen Ortiz Mellet, José M. García Fernández
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