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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
The aims for nanoparticle entrapment of drugs are either enhanced delivery to, or uptake by, target cells and/or a reduction in the toxicity of the free drug to non-target organs. Both situations will result in an increase of therapeutic index, the margin between the doses resulting in a therapeutic efficacy (eg,...Author: Wim H De Jong, Paul Ja Borm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322781/
Mar 24, 2015 · Nanoparticle formulations have been used in improving the bioavailability of various drugs, in particular, poorly soluble drugs. Nanoparticle drug delivery systems have found their unique applications in targeted drug delivery to tumors.Author: Byung Kook Lee, Yeon Hee Yun, Kinam Park
https://drug-dev.com/nanoparticles-a-revolution-in-the-development-of-drug-delivery-vehicles/
Nanoparticles, and liposomes in particular, have been used for drug delivery in cancer and inflammatory disease therapies for several years, but traditional manufacturing methods are labor intensive, hard to reproduce, and difficult to scale up.
https://manufacturingchemist.com/news/article_page/Nanoparticles_an_effective_means_of_drug_delivery/106763
For marketed products requiring lifecycle extension opportunities, nanoparticle formulation strategies provide a means to develop a new drug delivery platform with improved therapeutic outcome incorporating the existing drug, thus creating new avenues for addressing unmet medical needs.
https://www.entegris.com/content/en/home/resources/reference-materials/application-notes/appnote-drug-delivery-using-nanoparticles-10549.html
DRUG DELIVERY USING NANOPARTICLES Considerable research and development is devoted to improving drug delivery through the use of nanoparticles.
https://pubs.acs.org/doi/abs/10.1021/acs.iecr.9b04747
Abstract Significant efforts have been made to fabricate drug-loaded nanoparticles for drug delivery. Nanoprecipitation is a simple and versatile method for making various types of polymer nanoparticles with well-controlled particle size, size distribution, and surface properties.Author: Yun Liu, Guangze Yang, Da Zou, Yue Hui, Krishna D. P. Nigam, Anton Middelberg, Chun-Xia Zhao
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066374/
Dec 21, 2010 · Recent Advances in Lipid Nanoparticle Formulations with Solid Matrix for Oral Drug Delivery Surajit Das and Anumita Chaudhury Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research, 1 Pesek Road, Jurong Island, Singapore, 627833 Republic of …Author: Surajit Das, Anumita Chaudhury
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564463/
Nanoparticles were also incorporated into chitosan gel at different ratios for preparing a more suitable formulation for topical drug delivery with adequate viscosity. In ex-vivo permeation studies, nanoparticles increased the accumulation of DFV especially in the stratum corneum + epidermis of rat skin without any significant permeation.Author: I. Özcan, E. Azizoğlu, T. Senyiğit, M. Özyazıcı, Özgen. Özer
https://www.researchandmarkets.com/reports/553333/nanoparticle_drug_delivery_market_report
It is tailored for investors who plan to invest in the pharmaceutical industry with an eye towards how nanoparticle drug delivery technology will impact the economics of the pharmaceutical market. The information includes business summaries, technology core competencies, how nanoparticle adds value for investors in drug delivery companies ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768293/
Nov 01, 2005 · An alternative to these methods developed was drug nanoparticle formulation. The basic advantage of nanonization is increases in surface area and concentration gradient of these poorly soluble compounds followed by an increased dissolution rate of the compounds according to the Noyes-Whitney equation [ 13 ].Author: Lee Jia
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