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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559243/
NANOPARTICLE DELIVERY SYSTEMS IN CANCER VACCINES. ... Future examination of the ability of gelatin nanoparticle delivery systems to break tolerance to known TAAs will be of interest and might dictate whether these particles progress to clinical cancer vaccine trials. 6. NANOEMULSIONSAuthor: Yogita Krishnamachari, Sean M. Geary, Caitlin D. Lemke, Aliasger K. Salem
https://www.sciencedirect.com/science/article/pii/S0264410X13016319
The use of nanoparticles in vaccine formulations allows not only improved antigen stability and immunogenicity, but also targeted delivery and slow release. A number of nanoparticle vaccines varying in composition, size, shape, and surface properties have been approved for human use and the number of candidates is increasing.
https://www.mdpi.com/2076-393X/3/3/662
Nanomaterials with defined physico-biochemical properties are versatile drug delivery platforms that may address these key technical challenges facing cancer vaccines and immunotherapy. Nanoparticle systems have been shown to improve targeted delivery of tumor antigens and therapeutics against immune checkpoint molecules, amplify immune ...Author: Yuchen Fan, James J. Moon
https://www.researchgate.net/publication/45709591_Nanoparticle_Delivery_Systems_in_Cancer_Vaccines
Nanoparticle Delivery Systems in Cancer Vaccines Article · Literature Review (PDF Available) in Pharmaceutical Research 28(2):215-36 · February 2011 with 336 Reads How we measure 'reads'
https://link.springer.com/article/10.1007/s11095-010-0241-4
Aug 19, 2010 · Antigen-loaded nanocarriers are capable of being actively taken up by antigen-presenting cells (APCs) and have shown promising potential in cancer immunotherapy by initiating a strong immunostimulatory cascade that results in potent antigen-specific immune responses against the cancer. Such carrier systems offer versatility in that they can ...Author: Yogita Krishnamachari, Sean M. Geary, Caitlin D. Lemke, Aliasger K. Salem
https://www.ncbi.nlm.nih.gov/pubmed/26350600
Aug 27, 2015 · Nanomaterials with defined physico-biochemical properties are versatile drug delivery platforms that may address these key technical challenges facing cancer vaccines and immunotherapy. Nanoparticle systems have been shown to improve targeted delivery of tumor antigens and therapeutics against immune checkpoint molecules, amplify immune ...Author: Yuchen Fan, James J. Moon
https://www.sciencedirect.com/science/article/pii/S1549963418305239
The use of nanoparticles in vaccines is supported by the premise that a higher cellular uptake and an elevated interaction of antigens with the immune cells can be achieved by using an optimally-designed delivery system. 38 Vaccine delivery materials that have been examined for cancer immunotherapy include liposomes, polymers, nanoparticles, and hydrogels.8, 39 Nanoparticles based on proteins ...Author: Medea Neek, Tae Il Kim, Szu-Wen Wang
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