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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660903/
Sep 25, 2015 · The structure of the nanofibrous drug delivery system plays a key role in the drug release process. The fiber diameter, specific surface area, size and total volume of pores significantly influence the convection and diffusion of the liquid in which the nanofibers are immersed. Therefore, the drug release is also influenced.Author: Jakub Hrib, Jakub Sirc, Radka Hobzova, Zuzana Hampejsova, Zuzana Bosakova, Marcela Munzarova, Jiri M...
https://www.sciencedirect.com/science/article/abs/pii/S1773224719301017
Nanofiber-based drug-delivery systems are widely applicable for specific drug release, according to the target location and timing, to achieve the desired therapeutic effects. A nanofiber formulation is usually developed for a specific drug, and a change of drug can drastically affect the release kinetics from the same delivery system.Author: Saša Kajdič, Odon Planinšek, Mirjana Gašperlin, Petra Kocbek
https://www.sigmaaldrich.com/technical-documents/articles/materials-science/electrospun-nanofibers.html
Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration. 1-3 Recently, electrospinning techniques using high-voltage electrostatic fields to generate nanofibrous structures have been used to develop drug or protein-loaded electrospun nanofibrous constructs for use as a novel implantable delivery …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846037/
Apart from large diversity in colonic drug delivery systems, nanofibers containing drugs have been less considered in colon-target delivery systems. Various approaches can be used for preparation of nanofibers. Electrospinning is one of the most reliable techniques for nanofiber formation.Author: Akhgari A, Heshmati Z, Sharif Makhmalzadeh B
https://www.pharmaexcipients.com/electrospinning/dual-drug-loaded-nanofibers/
Dual drug-loaded coaxial nanofibers for the treatment of corneal abrasion Corneal abrasion is a scratch wound on the surface of the anterior segment of the eye, which can predispose a patient to corneal infection and scarring, particularly if the cut penetrates to the deep corneal layers.
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