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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660903/
Sep 25, 2015 · The structure of the nanofibrous drug delivery system plays a key role in the drug release process. The fiber diameter, specific surface area, size and total volume of pores significantly influence the convection and diffusion of the liquid in which the nanofibers are immersed. Therefore, the drug release is also influenced.Author: Jakub Hrib, Jakub Sirc, Radka Hobzova, Zuzana Hampejsova, Zuzana Bosakova, Marcela Munzarova, Jiri M...
https://www.beilstein-journals.org/bjnano/articles/6/198
The structure of the nanofibrous drug delivery system plays a key role in the drug release process. The fiber diameter, specific surface area, size and total volume of pores significantly influence the convection and diffusion of the liquid in which the nanofibers are immersed. Therefore, the drug release is also influenced.Author: Jakub Hrib, Jakub Sirc, Radka Hobzova, Zuzana Hampejsova, Zuzana Bosakova, Marcela Munzarova, Jiri M...
https://www.sigmaaldrich.com/technical-documents/articles/materials-science/electrospun-nanofibers.html
Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration. 1-3 Recently, electrospinning techniques using high-voltage electrostatic fields to generate nanofibrous structures have been used to develop drug or protein-loaded electrospun nanofibrous constructs for use as a novel implantable delivery …
https://www.sciencedirect.com/science/article/pii/B9780323429788000097
Currently, electrospun nanofibers (NFs) are extensively applied in drug delivery systems. NF formulations offer various advantages in drug delivery such as high drug loading efficiency, flexibility to be formulated in various shapes, high surface-to-volume ratio, and high porosity.Author: Vibhuti Agrahari, Vivek Agrahari, Jianing Meng, Ashim K. Mitra
https://www.intechopen.com/online-first/nanofibers-in-mucosal-drug-and-vaccine-delivery
Nanofibers have been extensively used for different biomedical applications including wound dressing, tissue engineering, and drug delivery. Among their fabrication methods, the introduction of electrospinning technique was an important step toward achieving the goal of large scale industrial production of nanofiber-based drug delivery systems used in mucosal applications.Author: Josef Mašek, Eliška Mašková, Daniela Lubasová, Roman Špánek, Milan Raška, Jaroslav Turanek
https://www.ncbi.nlm.nih.gov/pubmed/30033869
Recently, electrospun polymeric nanofibers have proven to be an interesting strategy for drug delivery systems application. The high surface-to-volume ratio of the fibers can improve some processes, such as cell binding and proliferation, drug loading, and mass transfer processes.Author: Erick José Torres-Martinez, José Manuel Cornejo Bravo, Aracely Serrano Medina, Graciela Lizeth Pérez...
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