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https://www.medtronic.com/us-en/healthcare-professionals/therapies-procedures/neurological/targeted-drug-delivery.html
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https://www.medtronic.com/us-en/patients/treatments-therapies/drug-pump-chronic-pain.html
Deer T, Chapple I, Classen A, et al. Intrathecal drug delivery for treatment of chronic low back pain; report from the National Outcomes Registry for Low Back Pain. Pain Med. 2004;5(1):6-13. 3
https://academic.oup.com/bjaed/article/14/1/27/336442
Sep 04, 2013 · Intrathecal drug delivery (ITDD) systems comprise an IT catheter connected to a drug reservoir, which may be externalized and connected to a pump, or fully implanted. Two groups of patients may benefit from ITDD: those with spasticity (baclofen) and those with refractory pain.Author: Louise Lynch
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234284/
Nov 10, 2014 · With regard to intrathecal (IT) therapy in particular, the recently reported failure of IT gabapentin to provide effective relief of chronic noncancer pain highlights the importance of another area of pain management: proper therapy selection for individual patients.15 The observed failure in this instance may have resulted, in part, from the intentionally broad patient selection criteria and ...Author: Michael F. Saulino, Philip S. Kim, Erik Shaw
https://www.ncbi.nlm.nih.gov/books/NBK538237/
Apr 30, 2019 · It is vital to recognize that chronic pain conditions for which intrathecal drug delivery is appropriate are optimally managed by an integrated health care team. Intrathecal therapy and management can substantially lower health care costs compared with conventional pain management, especially when there is a cessation of systemic opioids. To ...Author: Neal Shah, Devang Padalia
https://www.webmd.com/pain-management/guide/spinal-drug-delivery-systems
Pain relief through spinal drug delivery systems, also called intrathecal drug delivery systems, involves implanting a small pump or using a catheter that delivers medication directly to the ...
https://www.neurologyadvisor.com/topics/pain/updated-guidelines-on-intrathecal-therapy-for-pain/
Jan 19, 2017 · Deer TR, Prager J, Levy R, et al. Polyanalgesic Consensus Conference 2012: recommendations for the management of pain by intrathecal (intraspinal) drug delivery: report of an interdisciplinary ...
https://journals.lww.com/anesthesia-analgesia/fulltext/2020/02000/intrathecal_drug_delivery_systems_for_cancer_pain_.6.aspx
27. Deer TR, Levy R, Prager J, et al. Polyanalgesic Consensus Conference–2012: recommendations to reduce morbidity and mortality in intrathecal drug delivery in the treatment of chronic pain. Neuromodulation. 2012;15:467–482.
https://www.wmpllc.org/ojs/index.php/jom/article/view/997
Intrathecal drug delivery (ITDD) has been an option for the management of persistent pain since the 1980s. The discovery of opioid receptors in the central nervous system was the impetus for early attempts to deliver opioids intraspinally.
https://www.sciencedirect.com/science/article/pii/S0169409X20300120
Intrathecal (IT) administration, i.e., the injection of substances directly into cerebrospinal fluid (CSF) that fills the thecal sac, is a potentially powerful drug delivery approach. This route of administration can achieve a high concentration of therapeutic agent within the central nervous system (CNS) while minimizing off-target exposure ...Author: M.J. Fowler, J.D. Cotter, B.E. Knight, E.M. Sevick-Muraca, D.I. Sandberg, D.I. Sandberg, R.W. Sirian...
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