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https://pubs.acs.org/doi/10.1021/nn900480m
A broad array of water-insoluble compounds has displayed therapeutically relevant properties toward a spectrum of medical and physiological disorders, including cancer and inflammation. However, the continued search for scalable, facile, and biocompatible routes toward mediating the dispersal of these compounds in water has limited their widespread application in medicine. Here we demonstrate ...Author: Mark A Chen, Erik D Pierstorff, Robert Lam, Shu-you Li, Houjin Huang, Eiji Osawa, Dean Ho
https://pubs.acs.org/doi/abs/10.1021/nn900480m
A broad array of water-insoluble compounds has displayed therapeutically relevant properties toward a spectrum of medical and physiological disorders, including cancer and inflammation. However, the continued search for scalable, facile, and biocompatible routes toward mediating the dispersal of these compounds in water has limited their widespread application in medicine.Author: Mark A Chen, Erik D Pierstorff, Robert Lam, Shu-you Li, Houjin Huang, Eiji Osawa, Dean Ho
https://www.researchgate.net/publication/26299543_Nanodiamond-Mediated_Delivery_of_Water-Insoluble_Therapeutics
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https://www.nanowerk.com/spotlight/spotid=11278.php
Jun 22, 2009 · Posted: Jun 22, 2009: Nanotechnology approach for advanced drug delivery of water-insoluble therapeutics (Nanowerk Spotlight) A broad spectrum of therapeutics or effector molecules that address several areas of medicine, from inflammation, to cancer, and regenerative medicine, are insoluble in water (they are soluble primarily in solvents generally regarded as unsuitable for injection).
https://www.sciencedirect.com/science/article/pii/B9780857093400500084
8.1. Introduction. This chapter presents a brief overview of the potential of nanodiamonds as novel template for drug delivery and targeting. Drug delivery has typically focused on optimizing drug therapy by simplifying administration of drugs, improving effectiveness, and clinical safety.Author: A.E. Mengesha, B-B.C. Youan
https://www.sciencedirect.com/science/article/pii/S0142961213010193
Nanodiamonds-mediated doxorubicin nuclear delivery to inhibit lung metastasis of breast cancer. ... A NDs-mediated drug delivery system, DNX, was prepared and used to inhibit the lung metastasis of breast cancer. ... R. Lam, S.Y. Li, H. Huang, E. Osawa, et al.Nanodiamond-mediated delivery of water-insoluble therapeutics. ACS Nano, 3 (2009), pp ...Author: Jisheng Xiao, Xiaopin Duan, Qi Yin, Zhiwen Zhang, Haijun Yu, Yaping Li
https://stm.sciencemag.org/content/3/73/73ra21.full
Mar 09, 2011 · NDs are also able to bind various therapeutics and other reagents by both permanent covalent bonds and reversible ionic bonds. ... PEGylated nanographene oxide for delivery of water-insoluble cancer drugs. J. Am. ... Nanodiamond-mediated delivery of water-insoluble therapeutics.Author: Edward K. Chow, Xue-Qing Zhang, Mark Chen, Robert Lam, Erik Robinson, Houjin Huang, Daniel Schaffer,...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326739/
Mar 07, 2012 · Application in Drug Delivery Systems. Since CNTs and other nanomaterials were discovered, they have been widely applied in the design of drug delivery systems because of their small sizes, easy penetration through cells, and their special structures on the surface which allow a covalent or non-covalent bond to the chemicals with poor membrane permeability such as small molecule drugs, …Author: Ying Zhu, Jing Li, Wenxin Li, Yu Zhang, Xiafeng Yang, Nan Chen, Yanhong Sun, Yun Zhao, Chunhai Fan, ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418073/
Jul 19, 2012 · Purpose: Detonation nanodiamonds (NDs) are carbon-based nanomaterials that, because of their size (4–5 nm), stable inert core, alterable surface chemistry, fluorescence, and biocompatibility, are emerging as bioimaging agents and promising tools for the delivery of biochemical molecules into cellular systems.Author: Randeep Kaur, Jackson M Chitanda, Deborah Michel, Jason Maley, Ferenc Borondics, Peng Yang, Ronald E...
https://vpd.ms.northwestern.edu/people/alumni/shuyou-li,-ph.d..html
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