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https://www.sciencedirect.com/science/article/pii/B9780857093400500084
8.1. Introduction. This chapter presents a brief overview of the potential of nanodiamonds as novel template for drug delivery and targeting. Drug delivery has typically focused on optimizing drug therapy by simplifying administration of drugs, improving effectiveness, and clinical safety.Author: A.E. Mengesha, B-B.C. Youan
https://nano.materials.drexel.edu/research/nanodiamonds-for-drug-delivery-applications/
Nanodiamond powder is one of the most promising carbon nanomaterials for drug delivery applications. Diamond nanoparticles of ~5 nm in size offer a large accessible surface and tailorable surface chemistry; have unique optical, mechanical, and thermal properties; and are non-toxic.
https://pubs.acs.org/doi/abs/10.1021/mp400213z
Nanodiamond particles produced by detonation synthesis and having ∼5 nm diameter possess unique properties, including low cell toxicity, biocompatibility, stable structure, and highly tailorable surface chemistry, which render them an attractive material for developing drug delivery systems. Although the potential for nanodiamonds in delivery and sustained release of anticancer drugs has ...Author: Vadym N. Mochalin, Amanda Pentecost, Xue-Mei Li, Ioannis Neitzel, Matthew Nelson, Chongyang Wei, Tao...
https://www.uclahealth.org/u-magazine/nanodiamonds-deliver-chemotherapy-drugs-directly-to-brain-tumors
Researchers at UCLA’s Jonsson Comprehensive Cancer Center have developed an innovative drug-delivery system in which tiny particles called nanodiamonds are used to carry chemotherapy drugs directly into brain tumors. The new method was found to result in greater cancer-killing efficiency and fewer harmful side effects than existing treatments.
https://www.nanodiamond.co.il/drug-delivery
E.K. Chow, et al., Nanodiamond therapeutic delivery agents mediate enhanced chemoresistant tumor treatment, Sci. Transl. Med. 3 (73) (2011) 73ra21. Gong J, Steinsultz N and Ouyang M 2016 Nanodiamond based nanostructures for coupling nitrogen-vacancy centresto metal nanoparticles and semiconductor quantum dots Nat. Commun. 7 11820
https://www.sciencedirect.com/science/article/pii/S2095177919301467
Immobilization of proteins on nanodiamond is much in use for drug delivery. Properties of having high colloidal stability and enterosorbent potential in aqueous and non-aqueous media allow NDs to be efficiently used for the targeted drug delivery . But stability of the complexes is based on bonding of NDs with respective proteins.Author: Swati Chauhan, Neha Jain, Upendra Nagaich
https://www.tandfonline.com/doi/abs/10.1517/17425247.2015.992412
Aug 17, 2009 · Expert Opinion on Drug Delivery Volume 12, 2015 - Issue 5. Submit an article Journal homepage. 564 Views 61 CrossRef citations to date Altmetric Reviews Nanodiamond-mediated drug delivery and imaging: challenges and opportunities. V Vaijayanthimala Indian Institute of Sciences, ...Author: V Vaijayanthimala, Dong Keun Lee, Sue V Kim, Albert Yen, Nathaniel Tsai, Dean Ho, Huan-Cheng Chang, ...
https://www.ornl.gov/news/diamonds-deliver
Feb 24, 2017 · “You can fine-tune these dynamics with chemical functionalization on the nanodiamond surface, further enhancing its effectiveness,” said Goswami. The findings will likely guide future studies not only on the potential of nanodiamonds in drug delivery but also on fighting bacteria and treating viral diseases. Building the bridge
http://www.japsonline.com/admin/php/uploads/120_pdf.pdf
for development of effective drug delivery systems. Key words: Nanotechnology, nanomaterial, nanodiamond, drug delivery system. INTRODUCTION In recent years, a number of synthetic methods for the preparation of nanocrystalline diamond, “Nanodiamond” (ND), in the form of films and powders, have been developed
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