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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626933/
This article will focus on nanosized crystals in medical application. In drug delivery and clinical applications the technology to nanonize (ie, to reduce in size to below 1000 nm) is one of the key factors for modern drug therapy, now and in the years to come. Over the last ten years, the number of poorly soluble drugs has steadily increased.Author: Jens-Uwe A H Junghanns, Rainer H Müller
https://www.youtube.com/watch?v=5BOi13cytTY
Apr 03, 2018 · This is my presentation on Drug Delivery Systems class. This presentation is about nano drug delivery systems used on cancer treatment. By Eduardo Machado Martins.Author: Eduardo Martins
https://www.researchgate.net/publication/275226328_Nanocrystal_technology_for_drug_formulation_and_delivery
Nanocrystal technology for drug formulation and delivery Article (PDF Available) in Frontiers of Chemical Science and Engineering 9(1):1-14 · March 2015 with 1,741 Reads How we measure 'reads'
https://www.researchgate.net/publication/23458143_Nanocrystal_technology_drug_delivery_and_clinical_applications
Introduction Nanocrystals constitutes of 100% drug and considered as a “new drug” by Food and Drug Administration. It is proven to be an effective alternative for topical delivery of drug with ...
https://link.springer.com/article/10.1007%2Fs11705-015-1509-3
Jun 20, 2016 · With the development of modern technology like high throughput screening, combinatorial chemistry and computer aid drug design, the drug discovery process has been dramatically accelerated. However, new drug candidates often exhibit poor aqueous or even organic medium solubility. Additionally, many of them may have low dissolution velocity and low oral bioavailability. Nanocrystal …Author: Tzu-Lan Chang, Honglei Zhan, Danni Liang, Jun F. Liang
https://www.youtube.com/watch?v=0wFwXUhHu5c
Jul 01, 2015 · Getting sufficient therapeutic drugs to the precise disease cell would reduce the amount of medication required; reduce side effects; and enhance treatment. Mabe explores the use of nano-particles ...Author: TEDx Talks
https://www.sciencedirect.com/science/article/pii/S0168365914001758
Engineered nanocrystal technology: In-vivo fate, targeting and applications in drug delivery. ... Ophthalmic drug delivery is a challenging task owing to critical pharmacokinetic environment and physiological barriers of the eye that hinder the delivery of drugs .Author: Vivek K. Pawar, Yuvraj Singh, Jaya Gopal Meher, Siddharth Gupta, Manish K. Chourasia
https://pdfs.semanticscholar.org/b2a2/2c584acb2c980b608d2d415a50f285481b26.pdf
characteristics of drug nanocrystals, and to develop feasible nanocrystal applications for ocular and oral drug delivery purposes. Hence, develop-ability issues from the analytical difficulties of the drug dissolution behavior to the scale-ability of the nanocrystals were covered. A …
https://www.sciencedirect.com/science/article/pii/S0378517317310311
2.1. Nanocrystal delivery forms. Both nanocrystal forms and amorphous solid dispersions increase the amount of drug dissolved at the site of absorption, and they accomplish this by different mechanisms. Nanocrystal delivery relies on reduced particle size for increased solubility and dissolution rate (Möschwitzer et al., 2011). The Nernst ...Author: Scott V. Jermain, Chris Brough, Robert O. Williams
https://www.pharmaceuticalonline.com/doc/first-us-approval-for-elans-nanocrystal-formu-0001
Aug 30, 2000 · FDA's action represents the first approval for a drug using NanoCrystal, which in tablet form provides easier administration and storage than the currently marketed Rapamune oral solution. Developed by Elan's Elan Pharmaceutical Technologies' (EPT) division, NanoCrystal technology enables efficient delivery of drugs that are poorly water-soluble.
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