We have collected information about Mucosal Delivery Of Macromolecules for you. Follow the links to find out details on Mucosal Delivery Of Macromolecules.
https://www.sciencedirect.com/science/article/pii/0168365994901511
Mucosal delivery of macromolecules. Abstract. Low molecular weight heparin (LMWH), a glycosaminoglycan of approximately 6000 molecular weight, is currently used in the prevention of postsurgical thrombosis and in the treatment of deep vein thrombosis.Author: C.D. Ebert, S.J. Heiber, S.C. Dave, S.W. Kim, D. Mix
https://www.sciencedirect.com/science/article/pii/B9780444820273500080
Transmucosal delivery across the tissues of the oral cavity may be an attractive means for non-invasively administer ing such drugs. The mucosa of the oral cavity can be generally divided into two categories, keratinized (gingiva and palate) and nonkeratinized epithelial tissues (sublingual and buccal).Author: C.D. Ebert, S.J. Heiber, S.C. Dave, S.W. Kim, D. Mix
https://link.springer.com/article/10.1007%2Fs11095-014-1485-1
Aug 29, 2014 · However, the buccal mucosa still exhibits some permeability-limiting properties, and therefore various methods have been explored to enhance the delivery of macromolecules via this route, including the use of chemical penetration enhancers, physical methods, particulate systems and mucoadhesive formulations.Author: Thiago Caon, Thiago Caon, Liang Jin, M O Claudia Simoes, Raymond Stanley Norton, Joseph Nicolazzo
http://www.pharmtech.com/oral-delivery-macromolecular-drugs
Jul 02, 2018 · Oral delivery of macromolecule drugs Being able to deliver macromolecular IBD treatments orally would improve patient experience, avoid systemic exposure, and increase drug presence at disease sites. However, maintaining stability and activity in the GI is a significant challenge.
https://www.researchgate.net/publication/260681021_Novel_strategies_for_the_buccal_delivery_of_macromolecules
Abstract For years now, the delivery of small molecules through the buccal mucosal route has been described in the literature, but it has only been over the past decade that investigations into ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410172/
Feb 13, 2019 · Other variables also impact the feasibility of oral delivery of macromolecules. If the plasma half-life (t ½) is too short, it will not be economically viable to administer a peptide candidate in multiple daily oral doses, where safety, efficacy, and variability issues would also arise. Similarly, a large therapeutic index (TI) is important in the context of selecting potent macromolecules as oral …Author: Caroline Twarog, Sarinj Fattah, Joanne Heade, Sam Maher, Elias Fattal, David J. Brayden
Searching for Mucosal Delivery Of Macromolecules?
You can just click the links above. The data is collected for you.
