We have collected information about Microneedles Insulin Delivery for you. Follow the links to find out details on Microneedles Insulin Delivery.
https://www.sciencedirect.com/science/article/pii/S1773224715000714
The transdermal delivery of insulin using biodegradable MNs has recently received great attentions. There are a plethora of studies demonstrating the effectiveness of using biodegradable MNs to increase the transport of insulin. For examples, Ling & Chen studied the transdermal delivery of insulin using dissolving MN patch.Author: Song Xie, Zijing Li, Zongqin Yu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419303/
Dissolving microneedles encapsulating insulin have also been studied extensively in mice, diabetic rats and dogs. [115–116, 118, 120, 125]. This approach was shown to enable stable encapsulation of insulin and effective insulin delivery to reduce blood glucose levels. Hollow microneedles have been used for insulin delivery.Author: Yeu-Chun Kim, Yeu-Chun Kim, Yeu-Chun Kim, Jung-Hwan Park, Mark R. Prausnitz
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444834/
Jan 08, 2018 · The skin's outer stratum corneum provides an impenetrable barrier for insulin drug delivery.[ 3 ] To overcome this, micrometer-scale needle contains a unique technological approach to enhance drug permeation across the skin layer, which thereby enables better insulin delivery which would require infection for delivery.
https://www.sciencedirect.com/science/article/pii/S0169409X18300504
Introducing microneedles (MNs) to insulin delivery is promising to pave the way for modulating glucose level noninvasively of diabetes patients, as which born to be painless, easy to handle and no need of any power supply. In this work, we review the process of insulin delivery systems (IDSs) based on MN technology in terms of two categories ...Author: Xuan Jin, Dan Dan Zhu, Bo Zhi Chen, Mohammad Ashfaq, Xin Dong Guo
http://news.mit.edu/2019/orally-deliver-drugs-injected-1007
Oct 07, 2019 · Microneedle delivery Langer and Traverso have previously developed several novel strategies for oral delivery of drugs that usually have to be injected. Those efforts include a pill coated with many tiny needles, as well as star-shaped structures that unfold and can remain in the stomach from days to weeks while releasing drugs.
https://www.sciencedirect.com/science/article/pii/S0168365918305169
Microneedle technology has attracted great interest over the past 20 years, diverse types of MNPs have been designed to improve insulin delivery, such as solid MNPs, coating MNPs, dissolving MNPs, degradable MNPs, hollow MNPs, phase transition MNPs and …Author: Xiang Chen, Li Wang, Haojie Yu, Chengjiang Li, Jingyi Feng, Fazal Haq, Amin Khan, Rizwan Ullah Khan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779563/
This is the first study assessing the application of microneedles for insulin delivery in human subjects. We demonstrated in two subjects with type 1 diabetes that microneedles can be used to effectively reduce glucose levels in a less painful manner as compared to traditional catheter infusion sets.Author: Jyoti Gupta, Eric Ian Felner, Mark R. Prausnitz
https://www.sciencedirect.com/science/article/pii/S0169409X03002394
Insulin delivery: “poke with patch” Using solid microneedles of a different design, Martanto et al. delivered insulin to diabetic hairless rats in vivo. Microneedle arrays were inserted into the skin using a high-velocity injector and shown by microscopy to embed fully within the skin.Author: Mark R Prausnitz
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455430/
Initial studies on microneedle devices revealed that the needles can be inserted into the skin in a predictable manner. 29 The first reports of enhanced transdermal delivery of insulin in vivo regarded the use of solid microneedles for increasing insulin delivery and decreasing blood glucose levels. 30 Later, infusion in vivo and into human ...Author: Michael Hultström, Niclas Roxhed, Lina Nordquist
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152630/
Microdermabrasion can increase skin permeability to insulin at levels sufficient to reduce BGL. Viable epidermis is a barrier to insulin delivery such that removal of full epidermis enables significantly more insulin delivery than removal of stratum corneum alone.Author: Samantha Andrews, Jeong Woo Lee, Seong-O Choi, Mark R. Prausnitz
Searching for Microneedles Insulin Delivery?
You can just click the links above. The data is collected for you.
