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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401754/
Dec 12, 2018 · Implantable drug delivery device classification is not a straightforward task as there are a number of complex implants that will fall into hybrid categories. Nevertheless, implantable drug delivery devices can be broadly classified in two main groups: passive implants and active implants. ... Monolithic type implants are made from a polymer ...Author: Sarah A. Stewart, Juan Domínguez-Robles, Ryan F. Donnelly, Eneko Larrañeta
https://www.researchgate.net/publication/45437242_Monolithic_Controlled_Delivery_Systems_Part_I_Basic_Characteristics_and_Mechanisms
Basic characteristics and mechanisms of monolithic drug delivery systems were recently presented in a review [3] from the point of view of mathematical modelling the controlled drug release (CDR ...
https://ocw.mit.edu/courses/materials-science-and-engineering/3-051j-materials-for-biomedical-applications-spring-2006/lecture-notes/lecture19.pdf
Lecture 19 Drug Delivery: Controlled Release What do we mean by “controlled” release? ... Monolithic Devices Drug is released by diffusion out of a polymer matrix ... Eroding Monolithic Device Drug is incorporated into a bioerodible or dissolvable polymer matrix
https://journals.sagepub.com/doi/full/10.1177/2211068211428189
Jan 27, 2012 · Classes of reservoir-based polymer drug delivery systems. Medical Devices Coupled With Drug Delivery Systems An important influence in the development of stand-alone reservoir-based delivery systems is the implanted medical device coupled with extended drug delivery.Author: Wan-Wan Yang, Erik Pierstorff
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648939/
Nov 04, 2012 · Oral controlled release systems. Historically, oral drug administration has been the predominant route for drug delivery. It is known to be the most popular route of drug administration due to the fact the gastrointestinal physiology offers more flexibility in dosage form design than most other routes (Chen et al. 2010, Gupta and Robinson 1992, Maderuelo et al. 2011, Tongwen and Binglin 1998).Author: Ali Nokhodchi, Shaista Raja, Pryia Patel, Kofi Asare-Addo
https://wjpr.net/admin/assets/article_issue/1425551899.pdf
Drug Delivery System include Push pull osmotic pump, Osmotic brusting osmotic pump, Liquid oral osmotic system, Sandwiched osmotic tablets, Delayed delivery osmotic device, Monolithic osmotic system and Controlled porosity osmotic pump. Osmotic drug delivery devices are composed of an osmotically active drug core, which is
https://patents.google.com/patent/US3923939A/en
A process for improving the release kinetics of a monolithic active agent delivery device comprising a shaped body of a dispersion of particulate active agent, such as a drug, with a polymer matrix, such as ethylene/vinylacetate copolymer, by substantially reducing the initial burst of active agent from the device when it is placed in its environment of use.Author: Baker Richard W, Michaels Alan S, Theeuwes Felix
https://www.sciencedirect.com/science/article/pii/S0939641102000590
The monolithic matrix type transdermal drug delivery systems of pinacidil monohydrate (PM) were prepared by film casting technique on mercury substrate and characterised in vitro by drug release studies using paddle over disc assembly, skin permeation studies using Keshary and Chein diffusion cell on albino rat skin and drug-excipient interaction analysis.Author: M Aqil, Asgar Ali
https://www.sciencedirect.com/science/article/abs/pii/S0939641102000590
The monolithic matrix type transdermal drug delivery systems of pinacidil monohydrate (PM) were prepared by film casting technique on mercury substrate and characterised in vitro by drug release studies using paddle over disc assembly, skin permeation studies using Keshary and Chein diffusion cell on albino rat skin and drug-excipient interaction analysis.Author: M Aqil, Asgar Ali
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